Adorex 5 mg/ml (Pediatric Drops)
15 ml drop: ৳ 20.07
Medicine Details
| Category | Details |
|---|---|
| Generic | Domperidone maleate |
| Company | Ambee pharmaceuticals ltd |
| Also available as |
Title
- Adorex 5 mg/ml Pediatric Drop
Categories
- Medicine
- Gastrointestinal
- Nausea and Vomiting
- Parkinson's Disease
- Pediatric
Description
- Dopamine antagonist medication
- Treats dyspeptic symptom complex
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Restores normal motility and tone of the upper gastrointestinal tract
- Prevents regurgitation of gastric content
Color Options
- Clear liquid
Dosage Form
- Pediatric Drop
- Oral Suspension
- Tablet
Dosage & Administration
- Should be taken 15-30 minutes before meals
- Maximum daily dose for adults is 80 mg
- Dosage varies for dyspeptic symptoms and acute conditions
Age Group
- Adults
- Children
Pharmacology
- Dopamine antagonist
- Blocks dopamine receptors in the Chemoreceptor Trigger Zone and stomach
- Restores normal motility and tone of the upper gastrointestinal tract
Key Ingredients
- Domperidone
Interaction
- Concomitant administration of anticholinergic drugs may antagonize the antidyspeptic effect
- Antacids and antisecretory drugs should not be given simultaneously
- Main metabolic pathway is through CYP3A4
- Concomitant use of drugs that significantly inhibit CYP3A4 may result in increased plasma levels of domperidone
Contraindications
- Known hypersensitivity to the drug
- Neonates
- Gastrointestinal hemorrhage, mechanical obstruction, perforation
- Prolactin releasing pituitary tumor (prolactinoma)
Side Effects
- Transient intestinal cramps
- Rare extrapyramidal phenomena
- Increase in plasma prolactin level
- Possible occurrence of neurological side effects in infants
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Should only be used during the first trimester of pregnancy if justified by therapeutic benefit
- Excreted in breast milk of lactating rats
- Domperidone concentrations in breast milk are 4 times lower than corresponding plasma concentrations
Precautions & Warnings
- Use with caution in children due to increased risk of extra-pyramidal reactions
- Use with caution in patients with hepatic impairment
Special Populations
- Use in infants should be with great caution and under close medical supervision
- Use with caution in patients with liver disorders
- Use with caution in patients with severe renal insufficiency
Overdose Effects
- Symptoms may include drowsiness, disorientation, and extrapyramidal reactions
- Administration of activated charcoal and close observation of patients are recommended
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Molecular Formula
C22H24ClN5O2
Chemical Structure
https://medex.com.bd/storage/res/g-res-380-domperidone-maleate-chemical-structure-4Q6P0Z8laWrV7xnOkSMm.svg
Common Questions
- Used to treat nausea and vomiting
- Should be taken before meals
- May cause dizziness and sleepiness
- Avoid consuming alcohol when taking
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away
Dimensions
N/A
Usability Features
- Relieves nausea, vomiting, and indigestion
Technical Specifications
- Maximum daily dose for adults is 80 mg
- In dyspeptic symptoms: 10-20 mg for adults
- In acute and sub-acute conditions: 20 mg for adults
- By rectum in suppositories: 30-60 mg for adults
- Administration frequency may need to be reduced in patients with severe renal insufficiency
Material
N/A
Design Elements
N/A
Additional Functionality
N/A