Codex (30 mg+100 mg+1.25 mg)/5 ml (Syrup)

100 ml bottle: ৳ 50.00

Medicine Details

Indications

  • Symptomatic relief of upper respiratory tract disorders
  • Productive cough relief
  • Nasal decongestant
  • Histamine H1 receptor antagonist
  • Expectorant combination

Pharmacology

  • Pseudoephedrine as decongestant and bronchodilator
  • Guaifenesin as an expectorant
  • Triprolidine as an antihistamine
  • Norepinephrine release
  • Increased hydration of respiratory tract
  • Reduction of sputum viscosity

Dosage & Administration

  • Adult dosage: 10 ml three times a day
  • Children 6-12 years: 5 ml three times a day
  • Children 2-5 years: 2.5 ml three times a day
  • Physician’s advice for children under 2 years

Interaction

  • Potential interactions with sympathomimetic agents
  • May cause a rise in blood pressure
  • Reversal of hypotensive action with certain drugs

Contraindications

  • Known hypersensitivity to constituents
  • Cardiovascular disease including hypertension
  • Lower respiratory symptoms including asthma
  • Monoamine oxidase inhibitor (MAOI) therapy

Side Effects

  • CNS depression or excitation
  • Drowsiness
  • Sleep disturbances
  • Hallucinations
  • Skin rashes
  • Tachycardia
  • Dryness of mouth, nose, and throat

Pregnancy & Lactation

  • Limited data on use during pregnancy
  • Caution advised due to lack of specific data

Precautions & Warnings

  • May cause drowsiness
  • Avoid driving or operating machinery
  • Avoid alcohol or sedatives
  • Use caution in hypertension, heart disease, diabetes, hyperthyroidism, elevated intra-ocular pressure, prostatic enlargement, renal and hepatic impairment
  • Not for persistent or chronic cough without physician direction

Overdose Effects

  • Drowsiness, irritability, restlessness, lethargy
  • Gastrointestinal discomfort
  • Respiratory depression
  • Convulsion
  • Tremor
  • Tachycardia
  • Hypertension
  • Gastric lavage may be necessary

Therapeutic Class

  • Combined cough expectorants

Storage Conditions

  • Store below 25°C
  • Protect from light
  • Do not refrigerate

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