Doxilin 100 mg (Capsule)
Unit Price: ৳ 2.13 (100's pack: ৳ 213.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Ambee pharmaceuticals ltd |
Title and Category
- Doxilin
- Medicine
Functions
- Treatment of respiratory tract infections
- Treatment of gastrointestinal tract infections
- Treatment of chlamydial infections
- Treatment of sexually transmitted diseases
- Treatment of other infections
- Bacteriostatic antibiotic
- Alternate treatment for gonorrhea and syphilis
- Inhibition of protein synthesis
Materials
- Doxycycline Hydrochloride
Pharmacological Characteristics
- Broad-spectrum antibiotic
- Primarily bacteriostatic
- Effective against Gram-positive and Gram-negative bacteria
- Effective against spirochete, mycoplasma, rickettsia, and mycobacteria
- More active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains of Staphylococcus aureus
- Active against certain Gram-negative strains of bacteria
- Active against various anaerobes
- Active against Haemophilus influenzae
- Active against Nocardia, Chlamydia, Mycoplasma, and a wide range of Rickettsiae
- Active against spirochetes such as Borellia recurrentis, Treponema pallidum, and Treponema pertenue
- Active against Plasmodium falciparum
Dimensions
- Capsules
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Impaired absorption with antacids containing aluminum, calcium, or magnesium
- Impaired absorption with iron-containing preparations
- Impaired absorption with bismuth salicylate
- Decrease in half-life with barbiturates, carbamazepine, and phenytoin
- Reduced efficacy of oral contraceptives with concurrent use of tetracyclines
- Possible need for downward adjustment of anticoagulant dosages in patients on anticoagulant therapy
- Avoidance of concurrent use with penicillin
Contraindications
- Hypersensitivity to any tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anemia
- Eosinophilia
Pregnancy and Lactation
- Avoidance in pregnant women due to risk of staining and effects on bone growth in the fetus
- Entry into breast milk, necessitating avoidance in breastfeeding mothers
Precautions and Warnings
- Avoidance during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) to prevent permanent discoloration of teeth
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store in a cool and dry place, protected from light