Diphedan 30 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 30.46

Medicine Details

Category Details
Generic Phenytoin sodium
Company Ambee pharmaceuticals ltd
Also available as

Indications

  • Treatment of status epilepticus
  • Prevention and treatment of seizures during neurosurgery

Pharmacology

  • Acts as an anticonvulsant
  • Increases efflux of sodium ions
  • Stabilizes neuronal membranes
  • Acts as an antiarrhythmic
  • Suppresses ventricular pacemaker automaticity

Dosage & Administration

  • Adult dosage of 200 mg daily
  • Maximum adult dosage of 600 mg/day
  • Children's initial dosage of 5 mg/kg per day
  • Maintenance dosage for children

Drug Interaction

  • Potentiation with sedative drugs or ethanol
  • Enhances toxic effects of paracetamol, lithium
  • Increased risk of osteomalacia with acetazolamide
  • Effects with other medications and inhibitors

Contraindications

  • Contraindicated in patients hypersensitive to phenytoin and hydantoins

Side Effects

  • Skin rashes
  • Insomnia
  • Slurred speech
  • Nervousness
  • Dizziness
  • Headache

Precautions & Warnings

  • Periodic blood checking during prolonged treatment
  • Discontinuation if skin rashes appear
  • Caution in pregnancy and nursing mothers
  • Reported hyperglycemia

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of reach of children

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