Klion 400 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Ambee pharmaceuticals ltd |
| Also available as |
Product Title
Klion 400 mg Tablet
Categories
- Antibiotics
- Antiprotozoal Agents
- Amoebicides
- Antidiarrheal
Description
Klion 400 mg Tablet is indicated for the prevention and treatment of various infections caused by anaerobic bacteria, urogenital trichomoniasis, bacterial vaginosis, all forms of amoebiasis, giardiasis, acute ulcerative gingivitis, anaerobically infected leg ulcers, pressure sores, acute dental infections, antibiotic-associated pseudomembranous colitis, and for surgical prophylaxis.
Color Options
- White
Dosage Form
- Tablet
- Suspension
- Vaginal Gel
- Suppository
- IV Infusion
Dosage Instructions
- Varied dosages for different conditions and age groups
- Dosage varies based on the type of infection and age of the patient
Active Ingredient
Metronidazole
Pharmacological Classification
Imidazole class of antibacterial drug, antiprotozoal agent
Mode of Action
Metronidazole interacts with DNA of anaerobes, leading to bactericidal action
Interaction
- Disulfiram: Concurrent use can cause psychotic reactions
- Alcohol: Should be avoided during therapy and for at least 1 day afterwards
- Lithium: Metronidazole may increase plasma levels of lithium
- Cyclosporin: Co-administration requires close monitoring of serum levels
- Phenytoin or phenobarbital: May lead to increased elimination of Metronidazole
- 5-Fluorouracil: Metronidazole may reduce clearance of 5-fluorouracil
- Busulfan: Metronidazole may increase plasma levels of busulfan
Contraindications
Hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy Category
Category B (US FDA)
Pregnancy & Lactation
Caution advised for use during pregnancy and nursing
Precautions
- Regular hematological tests recommended for long-term use
- Caution advised for patients with hepatic encephalopathy
- Patients should be warned about darkening of urine
Special Populations
- Hepatic Impairment: Caution advised, dosage reduction may be necessary
- Renal Impairment: No routine dosage adjustment needed, efficient removal during hemodialysis
Overdose Effects
- Vomiting
- Ataxia
- Slight disorientation
- No specific antidote
- Symptomatic and supportive treatment recommended
Therapeutic Class
- Amoebicides
- Antidiarrheal Antiprotozoal
Storage Conditions
Store below 30°C, protect from light, keep out of reach of children
Commonly Asked Questions
- What is Klion 400 mg Tablet?: An antibiotic medication preventing the growth of bacteria and parasites
- Uses of Klion 400 mg Tablet: Treatment and prevention of various infections
- Side Effects: Diarrhoea, headache, weakness, painful urination, numbness, muscle weakness, mouth ulcer
- Improvement of Conditions: 1-2 days before improvement is seen
- Contraindications: Should not be used in certain conditions
- Safety during Pregnancy: Not recommended unless absolutely necessary
- Effectiveness of High Dose: May lead to increased chances of side effects