Valsan 80 mg (Capsule)
Unit Price: ৳ 9.80 (20's pack: ৳ 196.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Valsartan |
| Company | Mystic pharmaceuticals ltd |
Indications
- For hypertension
- To reduce hospitalizations in patients with congestive heart failure
- To reduce death in patients who developed congestive heart failure after myocardial infarction
Pharmacology
- Oral medication
- Angiotensin receptor blockers (ARBs)
- AT1 subtype antagonist
- Dilates blood vessels and reduces blood pressure
- Does not affect pulse rate
- High affinity for AT1 receptor
Dosage
- Hypertension: 80-160 mg once daily
- Maximum dose: 320 mg daily
- Heart failure: 40 mg twice daily, may be increased to 80-160 mg twice daily
- Post-Myocardial Infarction: 20 mg twice daily, increased to 160 mg daily if tolerated
Administration
- Should be taken on an empty stomach
- No initial dosage adjustment for elderly patients with mild to moderate renal and hepatic insufficiency
Interaction
- No clinically significant drug interactions found
- Highly protein bound
- Caution with potassium sparing diuretics or supplements
- No metabolic induction or inhibition expected
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Headache
- Dizziness
- Fatigue
- Abdominal pain
- Cough
- Diarrhea
- Nausea
- Hyperkalemia
- Impotency
- Reduced renal function
- Allergic reactions
- Dyspnea
- Constipation
- Back pain
- Muscle cramps
- Rash
- Anxiety
- Insomnia
- Vertigo
- Hypotension (if taken with diuretics)
Pregnancy & Lactation
- Not to be used in pregnancy
- Can cause injury or death to fetus
- Not known if excreted in human milk
- Consider discontinuing nursing or drug based on importance to mother
Precautions & Warnings
- Impaired Hepatic Function: Exercised caution in mild to moderate hepatic impairment
- Impaired Renal Function: Dosage reduction or discontinuation may be required
- Heart Failure and Myocardial Infarction: Caution when initiating therapy
Use in Special Populations
- Pediatric use: Safety and effectiveness not established
- Geriatric use: No overall difference in efficacy or safety observed
- Hepatic Impairment: Mild to moderate - Max: 80 mg once daily. Severe - Contraindicated.
Overdose Effects
- Likely manifestations: hypotension and tachycardia
- Treatment: place patient in supine position, intravenous infusion of normal saline if necessary
Therapeutic Class
- Angiotensin-ll receptor blocker
Storage Conditions
- Store between 15-30°C
- Protect from moisture and heat