Seduxen 5 mg (Tablet)

Unit Price: ৳ 0.65 (200's pack: ৳ 130.00)

Medicine Details

Category Details
Generic Diazepam
Company Ambee pharmaceuticals ltd
Also available as
Seduxen 10 mg injection

Product Title

  • Seduxen 5mg Tablets

Category

  • Anxiolytic
  • Anticonvulsant
  • Skeletal Muscle Relaxant

Description

  • Benzodiazepine derivative with anxiolytic, anticonvulsant, and muscle relaxant actions

Color Options

  • White

Available Dosage

  • 5mg

Indications

  • Treatment of mild to moderate anxiety
  • Control of acute alcohol withdrawal
  • Premedication for surgical procedures
  • Insomnia of hospitalized patients
  • Febrile convulsions

Function

  • Anxiolytic
  • Anticonvulsant
  • Muscle relaxant
  • Tranquilizer

Mode of Action

  • Binds to specific site on the GABA receptor
  • Potentiates the effect of GABA
  • Opens chloride ion channels into cells

Absorption Rate

  • Rapid and complete after oral administration

Peak Plasma Concentration Time

  • 15-90 minutes after oral administration
  • 1.5-2 hours after rectal administration

Mean Plasma Half-life

  • 30 hours

Plasma Protein Binding

  • 98-99%

Metabolism

  • Liver metabolism

Elimination

  • Excreted in urine and feces

Dosage & Administration

  • 2mg thrice daily for anxiety
  • 5-15mg at bedtime for insomnia associated with anxiety
  • 10mg for severe acute anxiety via IM/slow IV injection

Interaction Warnings

  • Avoid concomitant intake with alcohol
  • Increased sedation with concomitant use of neuroleptics
  • Seduxen clearance increased by phonobarbitone
  • Metabolism inhibition by Omeprazole and isoniazide

Contraindications

  • Myasthenia gravis
  • Pulmonary insufficiency
  • Respiratory depression
  • Hypersensitivity to benzodiazepine

Side Effects

  • Somnolence
  • Dizziness
  • Confusion
  • Ataxia

Pregnancy & Lactation

  • Crosses placental barrier
  • Passes into breast milk
  • US FDA pregnancy category D

Precautions & Warnings

  • Avoid prolonged use and abrupt withdrawal
  • Caution in respiratory disease
  • Caution in hepatic or renal impairment

Overdose Effects

  • Sedation
  • Muscle weakness
  • Respiratory depression
  • Coma
  • Death

Therapeutic Class

  • Benzodiazepine sedatives
  • Centrally acting Skeletal Muscle Relaxants
  • Primary anti-epileptic drugs

Storage Conditions

  • Store in a cool and dry place protected from light

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