Sera 50 mg (Tablet)
Unit Price: ৳ 4.02 (50's pack: ৳ 201.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Ambee pharmaceuticals ltd |
Title
- Sera
- Sertraline Tablets
Category
- Anti-depressant
- Prescription Medication
- Pharmaceutical Product
Dosage Form
- Tablets
Indications
- Treatment of Major Depressive Disorder (MDD)
- Treatment of Obsessive-Compulsive Disorder (OCD)
- Treatment of Panic Disorder (PD)
- Treatment of Post-Traumatic Stress Disorder (PTSD)
- Treatment of Social Anxiety Disorder (SAD)
- Treatment of Premenstrual Dysphoric Disorder (PMDD)
Pharmacology
- Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT
- Increased 5-HT concentrations at the synaptic clefts
- Facilitation of sustained 5-HT activity at the postsynaptic receptor sites
- Improvement of depression
- Reduction of Serotonin turnover in the brain
- Prolonged elimination half-life for once daily administration
Dosage and Administration
- Adult Starting Dose: 25-50 mg
- Adult Therapeutic Range: 50-200 mg
- Pediatric Starting Dose (ages 6-12): 25 mg
- Pediatric Therapeutic Range: 50-200 mg
- Recommended interval between dose changes: one week
- Premenstrual Dysphoric Disorder (PMDD) starting dosage: 50 mg/day
- Continuous administration for PMDD
- Intermittent administration for PMDD
- Dosage adjustment for non-responsive patients
Interaction
- Effects of co-administration with drugs highly bound to plasma proteins
- Potential adverse effects from protein displacement
- Interaction with drugs such as Cimetidine, Diazepam, Hypoglycemic drugs, Atenolol etc.
Contraindications
- Known hypersensitivity to Sertraline or any excipients
- Moderate to severe hepatic impairment
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy and Lactation
- Safety during human pregnancy not established
- Excretion in breast milk
- Effect on nursing infant not established
- Consideration of discontinuing breast-feeding if treatment is necessary
Precautions and Warnings
- Caution in case of liver problems
- Caution in case of kidney diseases
- Caution in case of seizures
- Caution in case of heart problems
- Caution in case of allergies
- Potential dizziness or drowsiness
- Caution in activities requiring alertness
- Caution in use with the elderly
- Avoid use after taking monoamine oxidase inhibitor in the last five weeks
- Risk of suicidal thinking and behavior change
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Do not store above 30°C
- Keep out of the reach of children