Valsartil 40 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Valsartan |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Reduce hospitalizations in congestive heart failure
- Reduce death after myocardial infarction with congestive heart failure
Pharmacology
- Belongs to angiotensin receptor blockers (ARBs)
- Blocks angiotensin II receptor
- Dilates blood vessels
- Reduces blood pressure
- Orally active
- Specific angiotensin II antagonist acting on the AT1 subtype
- Does not bind or block other hormone receptors or ion channels
Dosage
- Usual dose for hypertension: 80-160 mg once daily
- Maximum dose for hypertension: 320 mg daily
- Usual dose for heart failure: 40 mg twice daily, may increase to 80-160 mg twice daily
- Usual dose post-myocardial infarction: 20 mg twice daily, may increase to 160 mg daily if tolerated
Administration
- Should be taken on an empty stomach
Interaction
- No clinically significant drug interactions found
- No metabolic induction or inhibition of the cytochrome P450 system expected
- Concomitant use of potassium sparing diuretics or salt substitutes containing potassium may lead to increase in serum potassium
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Headache
- Dizziness
- Fatigue
- Abdominal pain
- Cough
- Diarrhea
- Nausea
- Hyperkalemia
- Impotency
- Reduced renal function
- Allergic reactions
- Dyspnea
- Constipation
- Back pain
- Muscle cramps
- Rash
- Anxiety
- Insomnia
- Vertigo
- Hypotension if taking diuretics
Pregnancy & Lactation
- Not to be used in pregnancy
- Not known whether excreted in human milk
Precautions & Warnings
- Exercised in patients with hepatic impairment including biliary obstructive disorder
- Dosage reduction or discontinuation may be required with pre-existing renal impairment
- Caution in initiating therapy in heart failure and post-myocardial infarction patients
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall difference in efficacy or safety in geriatric patients observed
Overdose Effects
- Manifestations may include hypotension, tachycardia, bradycardia
- Patient should be placed in supine position, given intravenous infusion of normal saline if necessary
Therapeutic Class
- Angiotensin-ll receptor blocker
Storage Conditions
- Store between 15-30°C
- Protect from moisture and heat