Nuloc 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Monicopharma ltd
Also available as
Nuloc 40 mg injection

Title and Categories

    • Product Name: Nuloc 20 mg Tablet
    • Category: Medicine
    • Subcategory: Gastrointestinal Medication

Dimensions

    Color Options

      Functions

        • Relief from Chronic Heartburn Symptoms: e.g. gastroesophageal reflux disease (GERD)
        • Healing of Erosive Esophagitis: e.g. damage caused by stomach acid
        • Maintenance of Healing of Erosive Esophagitis:
        • Eradication of Helicobacter Pylori Infection: e.g. in patients with duodenal ulcer disease
        • Treatment for Zollinger-Ellison Syndrome:
        • Relief from Acid-related Dyspepsia Symptoms:
        • Treatment for Duodenal & Gastric Ulcer:

      Materials

        Technical Specifications

          • Oral Dosage Form: Tablet or Capsule
          • Dosage for Healing of Erosive Esophagitis:
            • 20 mg Once Daily for 4-8 Weeks
            • 40 mg Once Daily for 4-8 Weeks
          • Dosage for Maintaining Healing of Erosive Esophagitis: 20 mg Once Daily
          • Dosage for Symptomatic GERD: 20 mg Once Daily for 4 Weeks
          • Dosage for Helicobacter Pylori Eradication:
            • Esomeprazole 40 mg Once Daily for 10 days
            • Amoxicillin 1000 mg Twice Daily for 10 days
            • Clarithromycin 500 mg Twice Daily for 10 days
          • Dosage for Zollinger-Ellison Syndrome:
            • 20-80 mg Once Daily (adjusted individually)
          • Dosage for Acid-related Dyspepsia: 20-40 mg Once Daily for 2-4 weeks
          • Dosage for Duodenal Ulcer: 20 mg Once Daily for 2-4 weeks
          • Dosage for Gastric Ulcer:
            • 20-40 mg Once Daily for 4-8 weeks
          • IV Injection or IV Infusion for GERD with Erosive Esophagitis:
            • 20 mg or 40 mg once daily for adult patients
            • 10 mg or 20 mg once daily for pediatric patients
          • IV Infusion for Risk Reduction of Rebleeding of Gastric or Duodenal Ulcers: Continuous infusion of 8 mg/h for 72 hours after 80 mg IV infusion
          • Storage Conditions: Temperature not exceeding 30°C, dry place, protect from light and moisture

        Design Elements

          Usability Features

            • Administration for Tablet or Capsule: Swallowed whole and taken one hour before a meal
            • Administration for Oral Suspension:
              • Mixed with 15 ml of water
              • Stirred well and thickened for 2 to 3 minutes
              • Should be administered within 30 minutes if through a nasogastric or gastric tube
            • IV Injection Administration: Prepared with 0.9% Sodium Chloride, administered intravenously over at least 3 minutes

          Indications

            • Relief from Chronic Heartburn Symptoms: e.g. GERD
            • Healing of Erosive Esophagitis:
            • Maintenance of Healing of Erosive Esophagitis:
            • Eradication of Helicobacter Pylori Infection:
            • Treatment for Zollinger-Ellison Syndrome:
            • Relief from Acid-related Dyspepsia Symptoms:
            • Treatment for Duodenal & Gastric Ulcer:

          Interaction

            • Metabolism in the Liver by CYP2C19 and CYP3A4:
            • Not Likely to Inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, 3A4:
            • No Clinically Relevant Interactions with Specific Drugs:
            • Potential Interference with Gastric pH-dependent Drug Absorption:

          Contraindications

            • Known Hypersensitivity to Formulation:

          Side Effects

            • Frequently Occurring Adverse Events:
              • Headache
              • Diarrhoea
              • Nausea
              • Flatulence
              • Abdominal Pain
              • Constipation
              • Dry Mouth

          Pregnancy & Lactation

            • Safety and Effectiveness in Pregnant Women: Not Established
            • No Teratogenic Effects in Animal Studies: Revealed
            • Lack of Studied Excretion of Esomeprazole in Milk:
            • Discontinuation of Breastfeeding Considered Essential:

          Precautions & Warnings

            • Symptomatic Response to Therapy Does Not Exclude Gastric Malignancy:
            • Instructions for Swallowing Capsules: At least one hour before meals
            • Use of Antacids: Permissible While Taking Nuloc

          Use in Special Populations

            • Pediatric Use: Safety and Effectiveness Not Established
            • Geriatric Use: No Overall Differences in Safety and Efficacy Observed
            • Hepatic Insufficiency: No Dosage Adjustment Recommended for Mild to Moderate Insufficiency
            • Renal Insufficiency: Expected Unaltered Pharmacokinetics

          Overdose Effects

            • Acute Toxicity in Rats: Lethal with reduced motor activity, respiratory changes, tremor, and convulsions
            • No Specific Antidote Known:
            • Expected Lack of Removal by Dialysis:

          Compound Summary

            • Molecular Formula: C17H19N3O3S

          Commonly Asked Questions

            • Use of Nuloc 20 mg Tablet: Proton Pump Inhibitor for Reducing Stomach Acid Production
            • Multiple Uses of Nuloc 20 mg Tablet:
              • Heartburn Relief
              • GERD Symptom Relief
              • Healing Erosive Esophagitis
              • Prevention of Erosive Esophagitis Recurrence

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