Valsartil 160 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Valsartan |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
- Reducing hospitalizations in patients with congestive heart failure
- Reducing death in patients who developed congestive heart failure after myocardial infarction
Pharmacology
- Belongs to a class of drugs called angiotensin receptor blockers (ARBs)
- Blocks angiotensin II receptor
- Dilates blood vessels and reduces blood pressure without affecting pulse rate
- Orally active and specific angiotensin II antagonist acting on the AT1 subtype
Dosage
- Usual dose for hypertension: 80 to 160 mg once daily, maximum dose: 320 mg daily
- Usual dose for heart failure: 40 mg twice daily, may be increased to 80-160 mg twice daily
- Usual dose for post-myocardial infarction: 20 mg twice daily, may be increased to 160 mg daily
Administration
- Should be taken on an empty stomach to avoid decreased absorption
Interaction
- No clinically significant drug interactions found
- Concomitant use of potassium sparing diuretics, potassium supplements, or salt substitutes containing potassium may lead to increase in serum potassium
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Headache
- Dizziness
- Fatigue
- Abdominal pain
- Cough
- Diarrhea
- Nausea
- Hyperkalemia
- Impotency
- Reduced renal function
- Allergic reactions
- Dyspnea
- Constipation
- Back pain
- Muscle cramps
- Rash
- Anxiety
- Insomnia
- Vertigo
- Hypotension
Pregnancy & Lactation
- Not to be used in pregnancy as it can cause injury and death to fetus
- Potential adverse effects on the nursing infant, decision should be made whether to discontinue nursing or discontinue the drug
Precautions & Warnings
- Care should be exercised in patients with mild to moderate hepatic impairment including biliary obstructive disorder
- Dosage reduction or discontinuation may be required with patients having pre-existing renal impairment
- Caution should be exercised when initiating therapy in patients with heart failure and post-myocardial infarction patients
Use in Special Populations
- Safety and effectiveness in pediatric patients have not been established
- No overall difference in the efficacy or safety in geriatric patients, but greater sensitivity of some elderly persons cannot be ruled out
Overdose Effects
- Manifestations of overdosage: hypotension, tachycardia
- Bradycardia could occur from parasympathetic (vagal) stimulation
- Supine position and intravenous infusion of normal saline may be necessary if excessive hypotension occurs
Therapeutic Class
- Angiotensin-ll receptor blocker
Storage Conditions
- Store between 15-30°C
- Protect from moisture and heat