Maclid 500 mg (Capsule)

Unit Price: ৳ 35.00 (3 x 3: ৳ 315.00)
Strip Price: ৳ 105.00

Medicine Details

Category Details
Generic Azithromycin dihydrate
Company Ethical drugs limited
Also available as
Maclid 250 mg capsule Maclid 200 mg suspension

Indications

  • Lower respiratory tract infections
  • Upper respiratory tract infections
  • Otitis media
  • Skin and soft tissue infections
  • Non-gonococcal urethritis
  • Cervicitis

Pharmacology

  • Oral administration
  • Absorption on empty stomach
  • High concentration in phagocytes
  • Tissue concentration over 50 times higher than plasma
  • Biliary excretion
  • Microbial protein synthesis interference
  • Activity against gram-positive and gram-negative microorganisms

Dosage

  • Adult dosage: 500mg once daily for 3 days
  • 500mg once on day 1 followed by 250mg for 4 days
  • Children dosage based on body weight
  • Azithromycin injection for adult patients with pneumonia or pelvic inflammatory disease
  • No established use in children under 16 years

Administration

  • Reconstitution procedure for suspension
  • Need to be taken at least 1 hour before or 2 hours after a meal

Interaction

  • Interactions with antacids, carbamazepine, cyclosporin, digoxin, ergot derivatives, methylprednisolone, theophylline, warfarin, terfenadine

Contraindications

  • Hypersensitivity to Azithromycin or macrolide antibiotics
  • Co-administration with ergot derivatives
  • Patients with hepatic diseases

Side Effects

  • Gastrointestinal side effects (nauseas, abdominal discomfort, vomiting, etc.)
  • Allergic reactions
  • Reversible elevations in liver transaminases
  • Rare cases of cholestatic jaundice
  • Transient mild reductions in neutrofil counts
  • Reversible hearing impairment in high doses over prolonged periods

Pregnancy & Lactation

  • Pregnancy Category B
  • Animal reproduction studies have shown no harm to fetus
  • Caution in use during pregnancy and lactation

Precautions & Warnings

  • Rare serious allergic reactions reported
  • Long period of observation and treatment required for serious reactions

Use in Special Populations

  • No dose adjustment in mild renal impairment
  • Caution in severe renal impairment
  • Not recommended in hepatic impairment
  • No evidence of effect on ability to drive or use machines

Overdose Effects

  • No data specific to Maclid
  • Typical symptoms of macrolide antibiotic overdose
  • Supportive measures and gastric lavage recommended

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C38H72N2O12
  • Chemical Structure Image URI

Common Questions about Maclid 500 mg Capsule

  • Action of Maclid 500 mg Capsule
  • Uses of Maclid 500 mg Capsule
  • Side Effects of Maclid 500 mg Capsule
  • Storage and disposal instructions
  • Potential to cause diarrhea
  • Safety of Maclid 500 mg Capsule
  • Classification as an antibiotic
  • If no improvement after 3 days, and worsening of symptoms
  • Quick Tips for usage

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