Maclid 200 mg/5 ml (Powder for Suspension)

Title

• Maclid 200 mg/5 ml Suspension

Categories

• Antibiotics
• Macrolide Antibiotics
• Infection Treatments

Indications

• Lower respiratory tract infections
• Upper respiratory tract infections
• Skin and soft tissue infections
• Non-gonococcal urethritis
• Cervicitis

Dosage

• 500 mg once daily orally for 3 days
• 500 mg once on day 1, then 250 mg once on days 2-5 for 4 days
• 1 gm given as a single dose for sexually transmitted diseases caused by Chlamydia trachomatis
• Oral dosage forms for adults and children
• Azithromycin Injection for adult patients with community-acquired pneumonia and pelvic inflammatory disease

Administration

• Reconstitution procedure for suspension
• Take at least 1 hour before or 2 hours after meal

Interaction

• Antacid interaction
• Carbamazepine interaction
• Cyclosporin interaction
• Digoxin interaction
• Ergot derivatives interaction
• Methylprednisolone interaction
• Theophylline interaction
• Warfarin interaction
• Terfenadine interaction

Contraindications

• Hypersensitivity to Azithromycin or macrolide antibiotic
• Co-administration of ergot derivatives
• Patients with hepatic diseases

Side Effects

• Gastrointestinal side-effects
• Allergic reactions
• Elevations in liver transaminases
• Cholestatic jaundice
• Reductions in neutrophil counts
• Reversible hearing impairment

Pregnancy & Lactation

• Category B for pregnancy
• No evidence on breastfeeding
• Caution during pregnancy and nursing

Precautions & Warnings

• Rare serious allergic reactions
• Caution in renal impairment
• Avoid use in hepatic impairment

Overdose Effects

• Typical symptoms of macrolide antibiotic overdosage
• Supportive measures recommended

Storage Conditions

• Keep in a dry place away from light and heat
• Keep out of the reach of children

Chemical Structure

• Molecular Formula: C38H72N2O12
• Chemical Structure Image available

Commonly Asked Questions

• Maclid 200 mg/5 ml Syrup purpose
• Uses of Maclid 200 mg/5 ml Syrup
• Side Effects of Maclid 200 mg/5 ml Syrup
• Storage and disposal instructions
• Diarrhea as a side effect
• Safety of Maclid 200 mg/5 ml Syrup
• Classification as an antibiotic
• Consultation advice for lack of improvement

Pharmacology

• Oral absorption characteristics
• Peak concentration time in adults
• High concentration in phagocytes
• Active transport to site of infection
• Biliary excretion as a major elimination route
• Microbiology action on specific organisms
• Binding to the 50S ribosomal subunit
• Lipid solubility characteristics

Use in Special Populations

• No dose adjustment needed in mild renal impairment
• Use caution in patients with more severe renal impairment
• Avoid use in patients with hepatic disease
• No reported effect on ability to drive or use machinery

Compound Summary

• Molecular Formula
• Chemical Structure available

Preparation Method

• Shake the bottle well to loosen the powder
• Add water up to the water mark of the bottle label
• Shake until powder is completely mixed with water

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