Almex 200 mg/5 ml (Oral Suspension)

10 ml bottle: ৳ 23.00

Medicine Details

Category Details
Generic Albendazole
Company Square pharmaceuticals plc
Also available as
Almex 400 mg chewable tablet

Title

  • Almex

Categories

  • Anthelmintic

Indications

  • Hookworm
  • Roundworm
  • Threadworm
  • Whipworm
  • Strongyloides
  • Tapeworm
  • Opisthorchi
  • Hydatid

Description

  • Benzimidazole anthelmintic
  • Vermicidal activity
  • Ovicidal activity
  • Larvicidal activity
  • Inhibitory effect on tubulin polymerization
  • Loss of cytoplasmic microtubules

Pharmacology

  • Broad spectrum anthelmintic
  • Blocking glucose uptake in helminths
  • Depleting energy levels in helminths
  • Immobilization of parasites
  • Metabolism in the liver
  • Poor absorption from gastrointestinal tract
  • Plasma half-life of about 8.5 hrs
  • Excretion in urine

Dosage & Administration

  • 400 mg single dose for various infections
  • 400 mg daily for strongyloidiasis or taeniasis
  • 200 mg single dose for children of 1-2 years
  • 400 mg twice daily for hydatid disease for patients over 60 kg
  • 15 mg/kg body weight daily for hydatid disease in patients less than 60 kg
  • 400 mg once daily for giardiasis for 5 days

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not for neonates
  • Possibly reduced dose for children under 10 kg
  • Avoid in pregnancy or suspected pregnancy
  • No alteration in dose needed for renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Liver enzyme changes
  • Rare reversible alopecia
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsions and meningism in cerebral disease

Pregnancy & Lactation

  • Albendazole FDA pregnancy category C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment and during each cycle
  • Caution in breastfeeding
  • Pregnancy exclusion before treatment
  • Constant medical supervision for Echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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