Prazomax 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Category Details
Generic Omeprazole
Company Social marketing company
Also available as
Prazomax 20 mg capsule

Indications

  • Treatment of gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks H+/K+ ATPase enzyme system
  • Onset of antisecretory effect occurs within one hour
  • Maximum effect occurs within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Substituted benzimidazole

Dosage

  • Oral dosage for various conditions
  • Dosages for pediatric use
  • Dosage for prophylaxis of acid aspiration in IV injection
  • Dosage for Zollinger-Ellison syndrome
  • Recommended dosage for Helicobacter pylori eradication regimen

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Instructions for IV administration
  • Reconstitution guidelines

Interaction

  • Decreased intragastric acidity affecting ketoconazole absorption
  • Metabolism in the liver through cytochrome P450
  • Potential interactions with diazepam, phenytoin, and warfarin
  • Plasma concentration increase during concomitant administration with clarithromycin
  • Absorption not affected by alcohol or food
  • Increased bioavailability of digoxin during simultaneous treatment

Contraindications

  • Known hypersensitivity
  • Possibility of malignancy in suspected gastric ulcer

Side Effects

  • Mild and reversible adverse reactions
  • Skin rash, urticaria, and pruritus
  • Diarrhea and headache
  • Gastrointestinal reactions including constipation and nausea/vomiting
  • Neurological effects like dizziness and paraesthesia
  • Reversible mental confusion, agitation, and depression
  • Arthritic and myalgic symptoms
  • Liver enzymes observation

Pregnancy & Lactation

  • Results from prospective epidemiological studies
  • No adverse effects of Omeprazole on pregnancy or fetus
  • No information on passage into breast milk
  • Use of Omeprazole during pregnancy
  • Discontinuation of breast-feeding if essential use of Omeprazole

Precautions & Warnings

  • Avoid concomitant use of clopidogrel and Prazomax
  • Increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted occasionally in long-term use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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