Fixim 100 mg/5 ml (Powder for Suspension)
50 ml bottle: ৳ 195.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Reman drug laboratories ltd |
| Also available as |
Indications
- Treatment of Upper Respiratory Tract Infections (URTI)
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections (UTI)
- Clinical efficacy against Streptococcus pneumonia
- Clinical efficacy against Streptococcus pyogenes
- Clinical efficacy against Escherichia coli
- Clinical efficacy against Proteus mirabilis
- Clinical efficacy against Klebsiella species
- Highly stable in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
- Interferes with the synthesis of bacterial cell wall
- Highly stable in the presence of beta-lactamase enzyme
- Approximately 40-50% absorption
Dosage & Administration
- Usual course of treatment is 7 days
- May be continued for up to 14 days if required
- Recommended adult dosage is 200-400 mg daily
- Recommended dosage for children is 8 mg/kg/day
- Special dosing for typhoid treatment
- Caution and dose adjustment in elderly and patients with renal impairment
Interaction
- Potential increase in prothrombin times in some patients
- Careful consideration needed for patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Mild and self-limiting adverse reactions
- Frequent gastrointestinal disturbances like diarrhea
- Other gastrointestinal side-effects include nausea, abdominal pain, and vomiting
- Central nervous system effects like headache and dizziness
- Hypersensitivity reactions in the form of rash and urticaria
- Hematological reactions such as thrombocytopenia and leukopenia
- Mild and reversible changes in liver and renal function tests
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Caution advised for use during pregnancy
- Unknown excretion in human milk
- Caution advised for use during lactation
Precautions & Warnings
- Caution in patients with known hypersensitivity to other drugs
- Cautious use in penicillin-sensitive patients
- Administration with caution in patients with markedly impaired renal function
- Potential alteration of normal flora of the colon with broad-spectrum antibiotics
Overdose Effects
- Gastric lavage may be indicated in case of overdose
- No specific antidote available
- Not significantly removed by hemodialysis or peritoneal dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Recommended storage below 30°C temperature
- Protection from light and moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
- Visual depiction of chemical structure available
Common Questions about Fixim 100 mg/5 ml Suspension
- Indication for treating bacterial infections
- Common uses for Urinary Tract Infections (UTI) and other conditions
- List of commonly reported side-effects
- Instructions for storage and disposal
- Limitations for treating cold and flu
- No specific dietary instructions
- Not recommended for treating diarrhea
- Safety information for infants and newborns
- Differentiation from penicillin variants
- Known side-effects of causing loose-motion and constipation
- No evidence of interaction with contraception
- Possible interaction with acetaminophen (Paracetamol)
- Time for onset of action and advice if symptoms persist
- Quick tips for dosage and potential side-effects