Esozyme 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Esomeprazole
Company Cosmic pharma ltd
Also available as
Esozyme 20 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Treatment of symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Treatment of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of duodenal and gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of H+/K+-ATPase in the gastric parietal cell
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Extensive metabolism in the liver by the cytochrome P450 (CYP) enzyme system
  • Systemic bioavailability of approximately 90%
  • Plasma elimination half-life of approximately 1–1.5 hours

Dosage

  • Oral dosage form
  • IV Injection and IV infusion for specific conditions
  • Dosage varies for different indications and patient categories

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension should be prepared and administered carefully
  • IV Injection should be given over a specific period of time

Interaction

  • Extensive metabolism in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs metabolized by specific CYP enzymes
  • Potential interference with absorption of drugs where gastric pH is important

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if esomeprazole use considered essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for patients to take capsules and tablets

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals

Overdose Effects

  • Lethal dose observed in animal studies
  • No specific antidote known, treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions about Esozyme 20 mg Capsule

  • Proton pump inhibitor reducing stomach acid production
  • Multiple uses for various conditions involving excess stomach acid
  • Common side effects like headaches, diarrhea, nausea, and more
  • Considerations for pregnant or breastfeeding individuals
  • Quick tips for taking Esozyme 20 mg Capsule

Related Brands