Apnac 50 mg (Tablet)
Unit Price: ৳ 0.80 (100's pack: ৳ 80.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Supreme pharmaceutical ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Sprain
- Bruises
- Dislocations
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication
- Post-operative pain relief
- Prevention of pain and inflammation in surgery
- Post-traumatic pain relief
- Treatment of renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Metabolized in the liver
- First pass metabolism
- Complete absorption from the gastrointestinal tract
- Peak plasma concentrations reached in about 2 hours
- 99.7% bound to plasma proteins
Dosage & Administration
- Diclofenac FC Tablet
- Diclofenac SR Tablet
- Diclofenac Dispersible Tablet
- Diclofenac TR Capsule
- Diclofenac Suppository
- Diclofenac injection
- Diclofenac Gel
- Daily dosage range of 75-150 mg for adults
- Dosage adjustment for long term use
- Specific dosage for children
- Recommended dosage for different formulations
Interaction
- Potential interactions with lithium and digoxin
- Possible risk of hemorrhage with anticoagulants
- Safe co-administration with oral antidiabetic agents
- Potential nephrotoxicity with cyclosporin
- Risks of toxicity when used with methotrexate
- Potential interaction with quinolone antimicrobials
- Increased frequency of side effects when co-administered with other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to non-steroid anti-inflammatory agents
- Contraindicated in asthmatic patients sensitive to acetylsalicylic acid or prostaglandin synthetase inhibitors
- Avoid use under occlusive dressings
Side Effects
- Mild, rare, and transient adverse effects
- Possible gastrointestinal discomfort at the start of treatment
- Peripheral edema
- Skin reactions like rash and eczema
- Local irritation and reddening of the skin with Gel application
Pregnancy & Lactation
- Use during pregnancy only for compelling reasons
- Lowest effective dose should be used during pregnancy
- Not recommended during the first trimester
- Insufficient data for use during pregnancy
- Insignificant quantity detected in breast milk with no expected adverse effects on the infant
Precautions & Warnings
- Close observation in patients prone to peptic ulceration or gastrointestinal bleeding
- Caution to avoid contact with eyes or mucous membranes
- Proper hand hygiene after application
- Oral ingestion should be avoided
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry storage
- Protection from light
- Storage below 30°C
- Keep out of the reach of children