D-Floxin 250 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 65.00

Medicine Details

Product Title

  • D-Floxin

Categories

  • Antibiotic
  • Anti-infective
  • Quinolone
  • Antimicrobial

Description

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of antibacterial activity
  • Indicated for various types of infections caused by susceptible organisms
  • Rapid and well absorption from the gastrointestinal tract
  • Widely distributed into body tissues and fluids
  • Significant concentration in serum, urine, and body tissues
  • Bactericidal action through interference with DNA gyrase enzyme
  • Dosage determined by infection severity, causative organism, age, weight, and renal function
  • Dosage range for adults: 100-750 mg twice daily
  • Different dosages for specific types of infections
  • Dosage adjustment in case of impaired renal function
  • Extended-release tablet recommended for acute cystitis
  • IV infusion dosage for various infections
  • Specific instructions for Ciprofloxacin IV infusion administration
  • Contraindicated in patients with hypersensitivity to Ciprofloxacin or other quinolones
  • Various potential side effects including gastrointestinal and central nervous system disturbances, hypersensitivity reactions, joint pain, and transient increased liver enzymes
  • Not recommended during pregnancy and lactation
  • Precautions for patients with CNS disorders and concurrent use with certain medications
  • Not a first-choice drug in pediatric population
  • Potential effects and complications of overdose
  • Belongs to the therapeutic class of 4-Quinolone preparations and Antibacterial antimicrobial drugs
  • Storage condition: Keep below 30°C, protected from light and moisture, out of reach of children

Indications

  • Treatment of single infection or mixed infections caused by susceptible organisms
  • Wide range of indicated infections including respiratory, urinary, gastrointestinal, skin, soft tissue, bone, joint, pelvic, eye, ear, nose, and throat infections
  • Effective against organisms resistant to other antibiotics
  • Suitable for use alone or in combination with other antibiotics
  • Effective for gonorrhea and septicaemia

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum of activity against gram-negative and gram-positive aerobic bacteria
  • Bactericidal action through interference with DNA gyrase enzyme
  • Rapid and well absorption from the gastrointestinal tract
  • Widely distributed into body tissues and fluids
  • Half-life of approximately 3.5 hours
  • Excretion of 30-50% of oral dose in urine within 24 hours

Dosage

  • Adult dosage range: 100-750 mg twice daily
  • Different dosages for specific types of infections
  • Dosage adjustment in impaired renal function
  • Extended-release tablet recommended for acute cystitis
  • IV infusion dosage for various infections
  • Duration of treatment depends on infection severity, clinical response, and bacteriological findings

Administration

  • Specific instructions for Ciprofloxacin IV infusion administration

Interaction

  • Avoid concurrent administration with Magnesium or Aluminum containing antacids, sucralfate, Calcium, Iron, or Zinc products
  • Avoid concurrent use with milk or dairy products
  • Dietary calcium in a meal does not significantly affect absorption

Contraindications

  • Hypersensitivity to Ciprofloxacin or other quinolones

Side Effects

  • Gastrointestinal disturbances
  • Central nervous system disturbances
  • Hypersensitivity reactions
  • Joint pain
  • Photosensitivity
  • Transient increase in liver enzymes
  • Hypoglycemia and mental health adverse effects

Pregnancy & Lactation

  • Not recommended during pregnancy due to potential arthropathy in immature animals
  • Secretion in milk, not recommended for nursing mothers

Precautions & Warnings

  • Use with caution in patients with CNS disorders
  • Dosage may be taken with or without meals
  • Specific precautions for concurrent administration with certain medications

Use in Special Populations

  • Not a first-choice drug in pediatric population

Overdose Effects

  • Seizures, hallucinations, confusion, renal and hepatic impairment, crystalluria, haematuria, reversible renal toxicity

Therapeutic Class

  • 4-Quinolone preparations
  • Antibacterial antimicrobial drugs

Storage Conditions

  • Keep below 30°C, protected from light and moisture, out of reach of children

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