Almoxil 250 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Aexim pharmaceuticals ltd |
| Also available as |
Title
Almoxil 250mg Capsule
Categories
- Antibiotics
- Penicillins
Description
Almoxil is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include ear, nose and throat infections, lower respiratory tract infections, skin and soft tissue infections, genito-urinary tract infections, venereal disease, dental abscess, H. pylori infection, and duodenal ulcer disease.
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- Dental abscess
- H. pylori infection
- Duodenal ulcer disease
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It inhibits biosynthesis of cell wall and is stable in the presence of gastric acid. Rapidly absorbed after oral administration.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
- SeverePurulentRespiratoryInfection: 3 gm every 12 hours
- OtitisMediaAdult: 1 g three times daily
- OtitisMediaChildren: 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- DentalAbscess: 3 gm, repeated after 10-12 hours
- UrinaryTractInfections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
- RenalImpairment: May require reduction in total daily dosage
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water.
Interaction
- Concurrent use of Almoxil and Probenecid may result in increased and prolonged blood levels. Almoxil may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
SideEffects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis (rare)
PregnancyAndLactation
US FDA pregnancy category B. Caution should be exercised when administered to lactating mothers.
PrecautionsAndWarnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.
TherapeuticClass
Broad spectrum penicillins
Reconstitution
- Intramuscular: Add 2.5 ml water for injection to Amoxicillin 500 mg injection vial
- Intravenous: Dissolve Amoxicillin 500 mg injection in 10 ml water for injection
StorageConditions
Keep in a dry place away from light and heat. Keep out of the reach of children.