Supraphen 10% (Ophthalmic Solution)
10 ml drop: ৳ 25.57
Medicine Details
| Category | Details |
|---|---|
| Generic | Chloramphenicol ophthalmic |
| Company | Gaco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of ocular infections involving the conjunctiva and/or cornea
- Infections caused by Supraphen-susceptible organisms such as Staphylococcus aureus, Streptococcus pneumoniae, E.coli, H. influenzae, Klebsiella/Enterobacter spp, Moraxella lacunata, and Neisseria species
Pharmacology
- Chloramphenicol as a broad-spectrum bacteriostatic antibiotic
- Inhibition of bacterial protein synthesis
- Interference with the transfer of activated amino acids from soluble RNA to ribosomes
Dosage & Administration
- Adult and children dosage: 1 or 2 drops in the conjunctival sac 4-6 times per day for the first 72 hours
- Subsequent dosage: 1 or 2 drops every 4 hours thereafter
- Treatment duration: Approximately 7 days
- Re-evaluation by physician: Recommended after 3 weeks
Interaction
- Inhibition of Chymotrypsin if given simultaneously with Supraphen
Contraindications
- Contraindicated in individuals with history of hypersensitivity to Chloramphenicol or any ingredients
Side Effects
- Frequent adverse reactions: Burning, stinging, conjunctival hyperemia
- Other reported adverse reactions: Blood dyscrasia, allergic or inflammatory reactions, vesicular and maculopapular dermatitis
Pregnancy & Lactation
- Use only when considered essential by physicians
- Safety not established for use in pregnancy and lactation
Precautions & Warnings
- Avoid use for minor infections or prophylaxis
- Repeated course and prolonged treatment should be avoided
- Possible blood dyscrasias after prolonged ophthalmic use
Overdose Effects
- Accidental ingestion unlikely to cause toxicity due to low antibiotic content
Therapeutic Class
- Ear Anti-Infectives & Antiseptics
- Eye Anti-Infectives & Antiseptics
- Macrolides
Storage Conditions
- Store in a cool place between 2°C-8°C
- Store in a dry place
- Protect from light
- Keep out of reach of children
- Do not touch dropper tip to surfaces
- Do not use after 30 days of opening