Lexopam 3 mg (Tablet)
Unit Price: ৳ 4.50 (5 x 10: ৳ 225.00)
Strip Price: ৳ 45.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Bromazepam |
| Company | Apex pharmaceuticals ltd |
Indications
- Emotional disturbances
- Acute tension and anxiety states
- Difficulties in interpersonal contact
- Agitation
- Insomnia
- Anxious and agitated depressive reactions
- Functional disturbances in the cardiovascular and respiratory systems
- Pseudoangina pectoris
- Pericardial anxiety
- Tachycardia
- Emotiogenic hypertension
- Dyspnea
- Hyperventilation
- Disturbances in the gastrointestinal tract
- Irritable bowel syndrome
- Epigastric pain
- Spasm
- Bloating diarrhea
- Disturbances in the urinary tract
- Frequency
- Irritable bladder
- Dysmenorrhea
- Psychosomatic disorder
- Psychogenic headache
- Asthma
- Gastric and duodenal ulcer
- Emotional reactions to chronic organic disease
Pharmacology
- Powerful psychotropic agent
- Selective reduction of tension and anxiety
- Sedative properties
- Muscle-relaxant properties
- Binds to the GABA-A receptor
- Produces a conformational change
- Potentiates inhibitory effects
Dosage
- Standard dosage 1.5-3 mg up to three times daily
- Severe cases dosage of 6-12 mg 2 or 3 times daily
- Overall treatment duration not more than 8-12 weeks
- Elderly and debilitated patients require lower doses
- Children dosage adjusted to low body weight (0.1-0.3 mg/kg)
Administration
- Oral administration
Interaction
- Enhanced sedative effects with other centrally active drugs
- Co-administration of cimetidine may prolong elimination half-life
- Concomitant intake with alcohol should be avoided
Contraindications
- Known hypersensitivity to bromazepam
- Severe respiratory insufficiency
- Severe hepatic insufficiency
- Sleep apnea syndrome
Side Effects
- Fatigue
- Drowsiness
- Muscle weakness
- Numbed muscle
- Reduced alertness
- Confusion
- Headache
- Ataxia
- Anterograde amnesia
Pregnancy & Lactation
- Safety during pregnancy not established
- Excreted in breast milk
Precautions & Warnings
- Development of physical and psychological dependence
- Greater risk in predisposed patients with a history of alcohol
- Withdrawal symptoms upon termination
- Recommended gradual dosage decrease upon termination
- Not recommended for primary treatment of sleeplessness caused by psychotic illness
- Caution while driving or using machinery
Therapeutic Class
- Benzodiazepine sedatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children