Nohist 10 mg (Tablet)
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Apex pharmaceuticals ltd |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic effects
- No significant antiserotonic effects
- Inhibition of histamine-mediated early phase of allergic reaction
- Reduction in migration of inflammatory cells
- Reduction in release of mediators associated with late phase of allergic reaction
- Peak plasma concentration of 257 mcg/L within one hour of administration
Dosage & Administration
- Adult dosage: 1 tablet or 2 teaspoonfuls daily
- Children 6+ years dosage: 1 tablet or 2 teaspoonfuls daily
- Children 2-6 years dosage: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
- Children 6 months to 2 years dosage: 1/2 teaspoonful once daily
- Recommended dosage regimen for injectable form once every 24 hours
Interaction
- No clinically significant drug interactions with Theophylline
- No clinically significant drug interactions with Azithromycin
- No clinically significant drug interactions with Pseudoephedrine
- No clinically significant drug interactions with Ketoconazole
- No clinically significant drug interactions with Erythromycin
Contraindications
- Contraindicated in patients with history of hypersensitivity to Cetirizine
- Contraindicated in patients with history of hypersensitivity to hydroxyzine
Side Effects
- Most common side effect: somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category: B
- Caution should be exercised when administered to nursing women
Precautions & Warnings
- Caution should be exercised when driving or operating heavy machinery
Use in Special Populations
- Reduced clearance and increased AUC in patients with mild to moderate hepatic impairment
- Reduced clearance and increased AUC in patients with mild to moderate renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children