Osovast 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Rosuvastatin calcium |
| Company | Apex pharmaceuticals ltd |
Indications
- Primary hyperlipidemia and mixed dyslipidemia
- Hypertriglyceredemia
- Dysbetalipoproteinemia (Type III hyperlipoproteinemia)
- Homozygous familial hypercholesterolemia (HoFH)
Pharmacology
Selective and competitive inhibitor of HMG-CoA reductase
Dosage & Administration
- Usual dose range of 5-20 mg/day
- Maximum recommended dose of 20 mg/day
- Recommended starting dose for homozygous familial hypercholesterolemia is 20 mg once daily
Interaction
- Cyclosporine
- Gemfibrosil
- Lopinavir/Ritonavir or atazanavir/ritonavir
- Coumarin anticoagulants
- Concomitant lipid-lowering therapies
Contraindications
- Known hypersensitivity to product components
- Liver disease
- Pregnant women
- Nursing mothers
Side Effects
- Headache
- Myalgia
- Constipation
- Asthenia
- Abdominal pain
- Nausea
Pregnancy & Lactation
Administered to women of childbearing age only when conceiving is highly unlikely
Precautions & Warnings
- Prescribed with caution in patients with predisposing factors for myopathy
- Discontinued if markedly elevated creatinine kinase levels occur
Overdose Effects
No specific treatment in the event of overdose
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
Keep below 30°C temperature, protected from light & moisture
Chemical Structure
Molecular Formula: C22H28FN3O6S
Common Questions about Osovast 10 mg Tablet
- Uses against Hyperlipidemia, Hypertriglyceridemia, Type 3 Hyperlipoproteinemia and Stroke
- Side effects include muscle pain, weakness, headache, and abdominal pain
Compound Summary
Image available for chemical structure
Quick Tips
- Treats high cholesterol by lowering LDL and triglycerides
- May cause diarrhea, gas, or an upset stomach, should be taken with food if any of these symptoms occur
- Inform doctor if experiencing fatigue, muscle weakness or pain
Dosage in Asian Patients
Initiation of therapy with 5 mg once daily should be considered for Asian patients
Use with Cyclosporine, Lopinavir/Ritonavir or Atazanavir/Ritonavir
Limit the dose of Rosuvastatin to 5 mg once daily in patients taking Cyclosporine
Concomitant Lipid-Lowering Therapy
Consider reduction in Rosuvastatin dosage when used in combination with Niacin or Fenofibrate
Dosage in Patients with Severe Renal Impairment
Start at 5 mg once daily and not exceed 10 mg once daily
Remarkable Drug Interactions
- Cyclosporine
- Gemfibrosil
- Lopinavir/Ritonavir or atazanavir/ritonavir
- Coumarin anticoagulants
- Concomitant lipid-lowering therapies
Heterozygous Familial Hypercholesterolemia in Pediatric Patients (10 to 17 years of age):
The usual dose range of Rosuvastatin is 5-20 mg/day; the maximum recommended dose is 20 mg/day
Very High Cholesterol and High Risk of Ml or Stroke
40 mg once daily
Interaction with Cyclosporine, Lopinavir/Ritonavir or Atazanavir/Ritonavir
Limit the dose of Rosuvastatin to 5-10 mg once daily
Concomitant Use with Gemfibrozil
Avoid combination therapy and limit the dose of Rosuvastatin to 10 mg once daily
Dosage Adjustments
Should be made at intervals of 4 weeks or more
Commonly Asked Questions
- What is Osovast 10 mg Tablet?
- What are the uses of Osovast 10 mg Tablet?
- What are the side effects of Osovast 10 mg Tablet?
- For how long should I take Osovast 10 mg Tablet?
- Does Osovast 10 mg Tablet cause weight gain?
- Does Osovast 10 mg Tablet make you tired?
- Should Osovast 10 mg Tablet be taken at night?
- What foods should be avoided when taking Osovast 10 mg Tablet?
- How do I know whether Osovast 10 mg Tablet is beneficial for me or not?
- Can Osovast 10 mg Tablet cause memory loss?
- Is it true that Osovast 10 mg Tablet can cause diabetes?
- Can I take alcohol with Osovast 10 mg Tablet?
Compound Summary Molecular Formula
C22H28FN3O6S
Compound Summary Chemical Structure
Image available for chemical structure