Apcetrim 400 mg+80 mg (Tablet)

Unit Price: ৳ 2.00

Medicine Details

Category	Details
Generic	Sulphamethoxazole trimethoprim
Company	Apc pharma ltd
Also available as	Apcetrim 200 mg suspension

Product Title

Cotrimoxazole Double Strength Tablet

Product Categories

Antimicrobial drugs
Sulphonamides & Trimethoprim
Therapeutic Class

Indications

Bactericidal activity
Gram-positive and Gram-negative organisms
Treatment of chronic bronchitis
Urinary tract infections
Respiratory tract infections
Genito-urinary tract infections
Gastro-intestinal tract infections
Chronic osteomyelitis
Skin infections
Septicaemia
Bacillary dysentery
Cholera treatment

Mode of Action

Broad spectrum bactericidal activity
Sequential blockade of bacterial enzyme systems
Biosynthesis of folinic acid
Gram-positive & gram-negative bacteria

Dosage & Administration

Dosage for mild to moderate infections
Dosage for severe infections
Long term therapy dosage
Dosage for gonorrhoea

Contraindications

Hypersensitivity to trimethoprim or sulphonamides
Megaloblastic anaemia
Liver parenchymal damage
Blood dyscrasia
Severe renal insufficiency
Glucose 6-phosphate dehydrogenase deficiency

Side Effects

Crystalluria
Allergic reactions
Haemolysis
Thrombocytopenia
Neutropenia
Agranulocytosis
Malaise
Headache
Nausea
Vomiting
Transient nature of side effects

Pregnancy & Lactation

Risk of passing through placenta and breast milk
Potential risk of kernicterus

Precautions & Warnings

Risk of macrocytic anaemia
Interference in the conversion of Folic acid
Reversal by giving Folinic acid
Caution with diabetic patients taking sulphonylurea drug

Storage Conditions

Temperature below 30°C
Protection from light & moisture
Keep out of the reach of children

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