Vildaglip 50 mg (Tablet)

Unit Price: ৳ 12.00 (2 x 10: ৳ 240.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Vildagliptin
Company Concord pharmaceuticals ltd

Indications

  • Adjunct to diet and exercise for type 2 diabetes mellitus
  • Improves glycemic control
  • Monotherapy
  • Dual combination therapy
  • Works with Metformin, Sulphonylurea, Thiazolidinedione, or Insulin

Pharmacology

  • Dipeptidyl peptidase-4 (DPP-4) inhibitor
  • Slows inactivation of incretin hormones
  • Regulates glucose homeostasis
  • Increases insulin release
  • Decreases glucagon levels

Dosage & Administration

  • Recommended daily doses of 50mg or 100mg
  • 50mg twice daily in dual combination with Metformin or Thiazolidinedione
  • 50mg once daily in the morning in dual combination with Sulphonylurea
  • May be taken with or without a meal
  • No dosage adjustment required for the elderly or patients with mild renal impairment
  • Not recommended for patients under 18 years of age

Interaction

  • No interactions with pioglitazone, metformin, glibenclamide, digoxin, warfarin, amlodipine, ramipril, valsartan, or simvastatin
  • Potential reduction in glucose-lowering effect by thiazides, corticosteroids, thyroid products, and sympathomimetics

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Moderate to severe renal impairment
  • Pre-treatment alanine aminotransferase (ALT) or aspartate aminotrasferase (AST) >3 times the upper limit of normal (ULN)
  • Type 1 diabetes

Side Effects

  • Majority of adverse reactions are mild and transient
  • Rare case of hepatic dysfunction
  • No additional safety signals in long-term use

Pregnancy & Lactation

  • Not to be used in pregnancy
  • Not to be used during lactation

Precautions & Warnings

  • Caution in patients aged 75 years and older
  • Monitoring of LFTs prior to initiation and periodically thereafter
  • Discontinuation if transaminase levels are increased
  • Consideration in congestive heart failure patients
  • Avoid use in NYHA functional class III IV

Therapeutic Class

  • Dipeptidyl Peptidase-4 (DPP-4) inhibitor

Storage Conditions

  • Store below 30°C temperature
  • Keep away from light & moisture
  • Keep out of reach of children

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