Iretavir 1 mg (Tablet)
Unit Price: ৳ 90.00 (1 x 10: ৳ 900.00)
Strip Price: ৳ 900.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Entecavir |
| Company | Genvio pharma ltd |
| Also available as |
Indications
- Treatment of chronic hepatitis B virus infection in adults
- Treatment of chronic hepatitis B virus infection in pediatric patients 2 years of age and older
- Evidence of active viral replication
- Evidence of persistent elevation in serum aminotransferases (ALT or AST)
- Histologically active disease
Pharmacology
- Competing with the natural substrate deoxyguanosine triphosphate
- Functional inhibition of all three activities of the HBV polymerase
- Base priming
- Reverse transcription of the negative strand from the pregenomic messenger RNA
- Synthesis of the positive strand of HBV DNA
- Inhibition of the HBV polymerase activity
Dosage & Administration
- Recommended dose of 0.5 mg once daily for adults and adolescents 16 years of age
- Recommended dose of 1 mg once daily for Lamivudine-refractory patients
- Recommended dose of 1 mg once daily for patients with decompensated liver disease (adult)
- Administration on an empty stomach
- Missed dose instructions
Interaction
- Co-administration with Lamivudine or Adefovir dipivoxil
- Effects on renal function and drug elimination
- Closely monitoring for adverse events
Contraindications
- Hypersensitivity to Entecavir or any component of the product
Side Effects
- Headache
- Fatigue
- Dizziness
- Nausea
Pregnancy & Lactation
- Unknown effect on the transmission of HBV from mother to infant
- Advice against breastfeeding while taking Entecavir
Precautions & Warnings
- Lactic acidosis and severe hepatomegaly with steatosis
- Exacerbations of hepatitis after discontinuation of treatment
Use in Special Populations
- Safety and effectiveness in pediatric patients below 2 years
- Limited clinical studies in subjects aged 65 years and over
- Dose adjustment in renal impairment
Overdose Effects
- No reported Iretavir overdosage in patients
- Limited adverse events in healthy subjects receiving high doses
- Monitoring for evidence of toxicity
- Standard supportive treatment
Therapeutic Class
- Hepatic viral infections (Hepatitis B)
Storage Conditions
- Dry place below 30°C
- Protected from light
- Keep out of the reach of children