Tolfenac SR 100 mg (Capsule (Sustained Release))
Unit Price: ৳ 3.00 (50's pack: ৳ 150.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Globex pharmaceuticals ltd |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Surgery and Traumatology
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Obstetrics and Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Otorhinolaryngology
- Pre-operative medication for the prevention of pain, inflammation, and swelling
- Dentistry
- Post-operative and post-traumatic pain, inflammation, and swelling
- Urogenital tract
- Renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Pronounced anti-rheumatic
- Analgesic
- Antipyretic properties
- Uricosuric effect
- Inhibiting prostaglandin biosynthesis
- Complete absorption from the gastro-intestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Adult dosage: 75-150 mg daily in 2 to 3 divided doses
- Preferably after food
- Children dosage: 1-3 mg of diclofenac/kg body weight daily in divided doses
- Elderly patients dosage: Lowest effective dosage recommended
- Maximum daily dose: 150 mg
- Diclofenac gel dosage: 2-4 g applied to the skin 3-4 times daily
- External use only
Interaction
- Drug interactions with Lithium and digoxin
- Anticoagulants
- Antidiabetic agents
- Cyclosporin
- Methotrexate
- Quinolone antimicrobials
- Other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient of the product
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Asthmatic patient with asthma, urticaria or acute rhinitis triggered by acetylsalicylic acid
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions
- Rash
- Eczema
- Local irritation
- Reddening of the skin
- Skin rash
Pregnancy & Lactation
- Used only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Peptic ulceration or gastrointestinal bleeding in rare instances
- Close observation for patients with advanced age
- Avoid contact with eyes or mucus membranes
- Hands should be washed after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children