Esolin 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Esomeprazole
Company Rephco pharmaceuticals ltd
Also available as
Esolin 40 mg tablet

Title

  • Esoin 20 mg Tablet

Categories

  • Medicine
  • Pharmacology
  • Gastrointestinal Health

Description

  • Indications:
    • Relief from chronic heartburn symptoms
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection
    • Treatment of Zollinger-Ellison Syndrome
    • Management of acid-related Dyspepsia
    • Treatment of Duodenal & Gastric ulcer
  • Pharmacology:
    • ModeOfAction: Proton pump inhibitor that suppresses gastric acid secretion
    • Absorption: Enteric-coated pellet formulation for controlled release
    • Distribution: 97% bound to plasma proteins
    • Metabolism: Extensive metabolism in the liver by CYP enzymes
    • Excretion: Less than 1% excreted in urine, remainder in faeces
  • Dosage:
    • OralDosageForm:
      • Healing of erosive esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
      • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
      • Zollinger-Ellison Syndrome: 20-80 mg once daily
    • IVInjectionOrInfusion:
      • AdultPatients: 20 mg or 40 mg once daily
      • PediatricPatients: Body weight <55 kg: 10 mg Once daily, Body Weight ≥55 kg: 20 mg once daily
  • Administration:
    • TabletOrCapsule: Swallowed whole and taken one hour before a meal
    • OralSuspension: Contents mixed with water and taken immediately
    • IVInjection: Administered over a period of at least 3 minutes
  • Interaction:
    • Metabolism: Metabolized in the liver by CYP2C19 and CYP3A4
    • Inhibition: Potential interference with CYP2C19 substrate metabolism
    • CombinationTherapy: Increased plasma levels of drug components
  • Contraindications: Hypersensitivity to any of the formulation
  • SideEffects: Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth
  • PregnancyAndLactation: No adequate and well-controlled studies in pregnant women. Excretion in milk not studied. Breastfeeding should be discontinued if essential
  • PrecautionsAndWarnings:
    • General: Symptomatic response does not preclude the presence of gastric malignancy
    • InformationForPatients:
      • Capsules should be taken at least one hour before meals
      • Use of antacids allowed while taking Esolin
  • UseInSpecialPopulations:
    • PediatricUse: Safety and effectiveness not established
    • GeriatricUse: No overall differences in safety and efficacy observed
    • HepaticInsufficiency: No dosage adjustment recommended for mild to moderate insufficiency
    • RenalInsufficiency: Pharmacokinetics not expected to be altered
  • OverdoseEffects:
    • Signs: Reduced motor activity, respiratory frequency changes, tremor, convulsions
    • Management: Symptomatic and supportive treatment
  • StorageConditions: Store at a temperature not exceeding 30°C, protect from light and moisture, keep out of reach of children
  • CompoundSummary:
    • MolecularFormula: C17H19N3O3S
    • ChemicalStructure: Viewable in the provided link
  • CommonlyAskedQuestions:
    • Uses:
      • Relief from heartburn and GERD symptoms
      • Aids in healing erosive esophagitis
      • Prevents erosive esophagitis recurrence
    • SideEffects: Headaches, diarrhea, nausea, gas, stomach pain, constipation, dry mouth
    • PregnancyAndBreastfeeding: Consult doctor about risks and benefits
    • TimeToWork: Usually starts working within a few hours of taking it

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