Mariprist 200 mg+200 mcg (Tablet)

(1+4) tablet kit: ৳ 300.00

Medicine Details

Category Details
Generic Mifepristone misoprostol
Company Renata limited

Indications

  • Early Menstrual Regulation (MR)
  • Termination of pregnancy up to 9 weeks gestation

Composition

  • 2 blister strips
  • 1 tablet of Mifepristone INN 200 mg
  • 4 tablets of Misoprostol USP 200 microgram each

Pharmacology

  • Mifepristone: Synthetic steroid with anti-progestational activity
  • Misoprostol: Synthetic analogue of prostaglandin E1

Dosage & Administration

  • Mifepristone administration
  • Misoprostol administration
  • Post-treatment examination

Interaction

  • Mifepristone metabolism
  • Effect of Misoprostol on aspirin

Contraindications

  • History of allergy to Mifepristone
  • Ectopic pregnancy
  • IUD in place
  • Haemorrhagic disorders
  • Inherited porphyria

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Headache
  • Dizziness

Pregnancy & Lactation

  • Risk of foetal malformation
  • Mifepristone excretion in breast milk
  • Misoprostol excretion in breast milk

Precautions & Warnings

  • Do not give to anyone else
  • IUD removal before treatment
  • Surgical termination recommended if treatment fails

Use in Special Populations

  • Decreased dose for hepatic impairment
  • Possible dose reduction for renal impairment

Overdose Effects

  • No serious adverse reactions in tolerance studies
  • Symptoms of Mifepristone overdose
  • Symptoms of Misoprostol overdose

Therapeutic Class

  • Drugs acting on the Uterus
  • Prostaglandin analogues

Storage Conditions

  • Store in a cool and dry place, protected from light

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