Aminomix 10% (IV Infusion)

500 ml bottle: ৳ 402.72

Medicine Details

Indications

  • Source of amino acids for protein synthesis
  • Suitable for patients with basal amino acid requirements
  • Faster recovery post-surgery
  • Effective management of cancer
  • Treatment for burns
  • Management of renal insufficiency and hepatic insufficiency

Composition

  • Amino acid solution with essential and non-essential amino acids
  • Contains electrolytes (sodium, potassium, magnesium, chloride, acetate)
  • Includes D-Sorbitol and non-essential amino acids
  • Total nitrogen content: 7.25 gm/L
  • Total energy content: 1551 kj/L (371.14 Kcal/L)

Pharmacology

  • Sterile aqueous solution of crystalline amino acids
  • Positive nitrogen balance for postoperative period
  • Clear, colorless to pale yellow colored solution
  • pH range of 5.0 to 7.0

Dosage & Administration

  • Dependent on patient's condition and metabolic stress
  • Infusion rates based on body weight
  • Slow infusion recommended
  • Recommended dosage range: 0.10-0.25 g nitrogen/kg/day
  • Dosage range corresponds to 15-35 ml IV/kg/day

Interaction

  • No significant pharmacological effects
  • No expected interactions with other medicaments

Contraindications

  • Inborn errors of amino acid metabolism
  • Severe liver dysfunction
  • Severe uremia without dialysis facilities
  • Hyperosmolar nonketotic diabetic coma

Side Effects

  • Rarely causes nausea
  • Possible vomiting, flushing, sweating at high infusion rates
  • Transient liver test increases reported
  • Potential hypersensitivity reactions
  • Thrombophlebitis risk with peripheral veins usage
  • Incidence of thrombophlebitis may be reduced with fat emulsion infusion
  • Hyperphenylalaninemia risk in severely ill, premature infants

Pregnancy & Lactation

  • Reported successful and safe administration during pregnancy in humans
  • No animal reproduction studies carried out

Precautions & Warnings

  • Increased urinary excretion of trace elements like copper and zinc
  • Monitoring of phenylalanine level in premature infants
  • Caution in patients with diabetes mellitus, severe heart failure, or renal function issues
  • Risk of thiamine deficiency syndrome in severely malnourished patients
  • Serum potassium and blood glucose monitoring recommended
  • Additional phosphate supply recommended for hypophosphatemia

Overdose Effects

  • Risk of nausea, vomiting, sweating with higher-than-recommended dosages
  • Thrombophlebitis risk with peripheral vein usage
  • Osmotic diuresis with dehydration risk
  • Symptoms related to hyperglycemia in case of overdose

Therapeutic Class

  • Parenteral nutritional preparations

Storage Conditions

  • Store at 15°C to 25°C temperature
  • Protect from light
  • Avoid freezing

Related Brands