Axinat-F (25 mcg+250 mcg)/puff (Inhaler)

120 metered doses: ৳ 752.00

Medicine Details

Category Details
Generic Salmeterol fluticasone propionate
Company Acme laboratories ltd
Also available as
Salflu 50 mcg inhalation capsule Salflu 50 mcg inhalation capsule Salflu 50 mcg inhalation capsule Salflu 25 mcg inhaler Salflu 25 mcg inhaler Axinat f 25 mcg inhaler

Indications

  • Regular treatment of asthma
  • Combination product for inadequately controlled asthma
  • Concurrent β-agonist and inhaled corticosteroid therapy

Pharmacology

  • Salmeterol Xinafoate as selective long-acting beta-2 agonist
  • Fluticasone Propionate as corticosteroid with glucocorticoid activity
  • Mechanism of action for Salmeterol
  • Mechanism of action for Fluticasone Propionate

Dosage

  • Dosage for adults and adolescents
  • Dosage for children (4-12 years)
  • Recommended starting dosages
  • Maximum recommended dosage
  • Dosage for pediatric patients

Administration

  • Use of Inhaler
  • Steps for effective Inhaler use
  • Instructions for cleaning Inhaler

Interaction

  • Avoidance of non-selective and selective β-blockers
  • Potential interaction with strong CYP3A4 inhibitors

Contraindications

  • Hypersensitivity to salmeterol xinafoate or fluticasone propionate
  • Primary treatment of status asthmaticus

Side Effects

  • Adverse reactions associated with Salmeterol
  • Adverse reactions associated with Fluticasone Propionate
  • Incidence of additional adverse events following concurrent administration

Pregnancy & Lactation

  • Consideration during pregnancy
  • Consideration during lactation
  • Reproductive toxicity studies in animals
  • Concentrations in human breast milk

Precautions & Warnings

  • Initiation during exacerbation
  • Use in asthma patients
  • Serious asthma-related adverse events
  • Paradoxical Bronchospasm
  • Increased reporting of pneumonia in COPD patients
  • Systemic effects of corticosteroids inhaled

Use in Special Populations

  • Reduction in growth velocity in paediatric patients

Overdose Effects

  • Signs and symptoms of Salmeterol overdose
  • Signs and symptoms of Fluticasone Propionate overdose
  • Monitoring of adrenal reserve in cases of Fluticasone Propionate overdose

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants
  • Respiratory corticosteroids

Storage Conditions

  • Precautions for pressurised canister
  • Storage temperature below 30°C
  • Avoidance of direct sunlight or heat

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