Defrol OFT 2000 IU (Flash Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Vitamin D3 deficiency
  • Calcium absorption
  • Phosphate absorption
  • Preventing rickets
  • Preventing osteomalacia
  • Preventing osteoporosis
  • Preventing pre-eclampsia
  • Immunity boost

Pharmacology

  • Active form: Calcitriol
  • Binding to Vitamin D receptors
  • Fat soluble
  • Absorption in small intestine
  • Metabolism in liver and kidney
  • Half life of 50 days
  • Storage in tissues
  • Elimination via feces and urine

Dosage & Administration

  • Adult dosage
  • Children dosage
  • Capsule administration
  • Film-coated tablet administration
  • Oroflash/chewable tablet administration
  • Syrup administration
  • Injection administration

Interaction

  • Drugs causing deficiency
  • Interference with absorption
  • Increased need with corticosteroids

Contraindications

  • Hypercalcaemia
  • Hypersensitivity
  • Toxicity evidence

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised calcium concentration
  • Raised phosphate concentration

Pregnancy & Lactation

  • Safe use during pregnancy
  • Recommended daily intake for pregnant women
  • Excretion in breast milk
  • Overdose in breast-fed infants
  • Variation in requirements

Precautions & Warnings

  • Plasma-calcium concentration monitoring
  • High doses monitoring
  • Renal impairment caution
  • Digoxin user consultation
  • Thiazide diuretics user consultation
  • Liver disease caution
  • Kidney disease caution
  • Primary hyperthyroidism caution
  • Lymphoma caution
  • Tuberculosis caution
  • Granulomatous disease caution

Use in Special Populations

  • Safety & efficacy in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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