Natrilix SR 1.5 mg (Tablet (Sustained Release))

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Indapamide
Company Servier bangladesh operation

Indications

  • Treatment of essential hypertension
  • Treatment of hypertension in patients with renal function impairment
  • Treatment of salt and fluid retention associated with congestive heart failure

Pharmacology

  • Diuretic antihypertensive
  • Vasodilation effect
  • Inhibition of ion passage across membranes
  • Reduction in vascular hyperreactivity
  • Decrease in total peripheral and arteriolar resistance

Dosage & Administration

  • One tablet daily in the morning
  • Combination with other categories of anti-hypertensive agents in severe cases
  • Safety and effectiveness not established in pediatric patients

Interaction

  • Potentiation of other antihypertensive drugs
  • Decrease in arterial responsiveness to norepinephrine
  • Reduced renal clearance and risk of toxicity when used with lithium

Contraindications

  • Hypersensitivity to sulfonamides
  • Severe renal failure
  • Hepatic encephalopathy or severe hepatic failure
  • Hypokalaemia

Side Effects

  • Headache
  • Anorexia
  • Gastric irritation
  • Nausea
  • Vomiting
  • Constipation
  • Diarrhoea

Pregnancy & Lactation

  • Not recommended for pregnant women
  • Not recommended for breastfeeding mothers

Precautions & Warnings

  • Monitoring of potassium and uric acid serum levels recommended
  • Close monitoring for patients with a history of allergy to sulfonamide derivatives
  • No reported allergic manifestations during clinical trials

Overdose Effects

  • Allergies
  • Skin rashes
  • Epigastric pain
  • Nausea
  • Photosensitivity
  • Dizziness
  • Weakness
  • Paraesthesia
  • Supportive and symptomatic treatment
  • Correction of electrolyte abnormalities

Therapeutic Class

  • Thiazide diuretics & related drugs

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture

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