Gluco-A 100 mg (Tablet)
Unit Price: ৳ 20.07 (1 x 10: ৳ 200.70)
Strip Price: ৳ 200.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Acarbose |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- For adults with type 2 diabetes mellitus
Pharmacology
- Inhibits pancreatic alpha-amylase
- Inhibits intestinal alpha-glucosidase enzymes
- Delays glucose absorption
- Lowers postprandial hyperglycemia
- Enhances glycemic control
- Diminishes insulinotropic and weight-increasing effects of sulfonylureas
- No inhibitory activity against lactase
Dosage & Administration
- Recommended starting dosage of 25 mg
- Given orally three times daily
- Gradual dose titration to minimize gastrointestinal side effects
- Dosage adjustment at 4–8 week intervals
- Maintenance dosage ranges from 50 mg to 100 mg three times daily
Interaction
- Some drugs may produce hyperglycemia
- May lead to loss of blood glucose control
- Close observation needed when co-administered with certain drugs
- Withdrawal of certain drugs may lead to hypoglycemia
- Potential for hypoglycemia when co-administered with sulfonylureas or insulin
Contraindications
- Hypersensitivity to the drug
- Diabetic ketoacidosis
- Cirrhosis
- Inflammatory bowel disease
- Colonic ulceration
- Partial intestinal obstruction
- Chronic intestinal diseases with digestion or absorption disorders
- Conditions that may deteriorate due to increased gas formation in the intestine
Side Effects
- Diarrhea
- Gas
- Upset stomach
- Constipation
- Stomach pain
Pregnancy & Lactation
- Pregnancy Category B
- No established safety in pregnant women
- Not recommended for nursing women
Precautions & Warnings
- Should not cause hypoglycemia when administered alone
- May increase potential for hypoglycemia when co-administered with sulfonylureas or insulin
- Use oral glucose instead of sucrose for hypoglycemia correction
- Severe hypoglycemia may require intravenous glucose infusion or glucagon injection
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No significant differences observed in geriatric use
Overdose Effects
- Transient increases in flatulence, diarrhea, abdominal discomfort
- No hypoglycemia result from overdose
- Avoid carbohydrates for 4–6 hours in case of overdose
Therapeutic Class
- Alpha-Glucosidase inhibitor
Storage Conditions
- Store below 25°C
- Protect from moisture