Tibofem 2.5 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Tibolone
Company Acme laboratories ltd

Indications

  • Treatment of symptoms resulting from natural or surgical menopause
  • Prevention of osteoporosis in postmenopausal women at high risk of fractures

Pharmacology

  • Tibolone is a synthetic steroid with estrogenic, androgenic, and progestagenic properties
  • Rapid metabolism into three compounds with different pharmacological effects
  • Substitutes for the loss of estrogen production in postmenopausal women
  • Alleviates menopausal symptoms
  • Prevents bone loss following menopause or ovariectomy

Dosage & Administration

  • One Tibolone tablet per day (2.5 mg daily)
  • Swallowed with water or other drink at the same time each day
  • Improvement of symptoms generally occurs within a few weeks
  • Optimal results after at least 3 months of therapy
  • Specific starting and switching instructions
  • Guidance on missed dose

Interaction

  • No reported interactions with other medicines in clinical practice
  • Theoretical interactions with enzyme-inducing compounds and anticoagulants

Contraindications

  • Pregnancy and lactation
  • Known or suspected hormone-dependent tumors
  • Cardiovascular or cerebrovascular disorders
  • Active deep vein thrombosis
  • Thromboembolic disorders
  • Vaginal bleeding of unknown etiology
  • Severe liver disorders

Side Effects

  • Occasional vaginal bleeding or spotting
  • Headache and migraine
  • Oedema
  • Dizziness
  • Pruritus
  • Increase in body weight
  • Nausea
  • Abdominal pain
  • Rash
  • Depression

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Treatment should be withdrawn immediately if pregnancy occurs
  • No available clinical data on exposed pregnancies
  • Contraindicated in lactating women

Precautions & Warnings

  • Patients with renal dysfunction
  • History of liver disease
  • Epilepsy
  • Migraine
  • Hypercholesterolemia
  • Impaired carbohydrate metabolism
  • Diabetes mellitus
  • Cholestatic jaundice

Overdose Effects

  • Low acute toxicity in animals
  • Expected symptoms in cases of acute overdose
  • Potential for nausea, vomiting, and withdrawal bleeding in females
  • Symptomatic treatment if necessary

Therapeutic Class

  • Drugs for menopausal symptoms
  • Hormone replacement therapy

Storage Conditions

  • Keep in a cool & dry place
  • Protect from light
  • Keep out of the reach of children

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