Coveram 4 mg+5 mg (Tablet)
Unit Price: ৳ 22.00 (3 x 10: ৳ 660.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Perindopril arginine amlodipine |
| Company | Servier bangladesh operation |
| Also available as |
Indications
- Treatment of hypertension
- Treatment of stable coronary heart disease
- Substitution therapy for perindopril and amlodipine
Pharmacology
- Perindopril hydrolysis to perindoprilat
- Inhibition of ACE
- Decreased plasma angiotensin II
- Amlodipine as calcium antagonist
- Inhibition of calcium ion influx
- Negative inotropic effects
Dosage & Administration
- Recommended daily dosage
- Single tablet per day
- Preferably taken in the morning
- Recommended to be taken before a meal
- Dose adjustments based on clinical judgment
Interaction
- Increased antihypertensive effect
- Blood pressure and renal function monitoring
- Possible hypotensive effects with other medicines
- Caution with combined use of nitroglycerine
Contraindications
- Hypersensitivity to active ingredients
- Contraindicated during pregnancy
- Contraindicated for lactating women
Side Effects
- Oedema
- Somnolence
- Dizziness
- Headache
- Dysgeusia
- Paraesthesia
- Visual impairment
- Tinnitus
- Vertigo
- Palpitations
- Flushing
- Hypotension
- Dyspnoea
- Cough
- Abdominal pain
- Nausea
- Vomiting
- Dyspepsia
- Diarrhoea
- Constipation
- Pruritus
- Rash
- Joint swelling
- Muscle spasms
- Fatigue
- Asthenia
Pregnancy & Lactation
- Not to be initiated during pregnancy
- Not to be used during lactation
- Alternative treatments recommended for pregnancy
Precautions & Warnings
- Contains lactose monohydrate
- Galactose intolerance precautions
- Serum electrolyte monitoring
Use in Special Populations
- Not recommended for use in children
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 25⁰C
- Keep container tightly closed
- Protect from light