Tazopen (2 gm+0.25 gm)/vial (IV Infusion)

2.25 gm vial: ৳ 550.00

Medicine Details

Category Details
Generic Piperacillin tazobactam
Company Renata limited
Also available as
Tazopen 4 gm injection

Title

  • Piperacillin and Tazobactam Combination Product

Categories

  • Antibacterial
  • Beta-Lactamase Inhibitor
  • Intravenous Infusion
  • Antibiotic
  • Pharmaceutical

Description

  • This product has a combination of piperacillin, a penicillin-class antibacterial, and tazobactam, a beta-lactamase inhibitor. It is indicated for the treatment of moderate to severe infections caused by susceptible bacteria in various conditions.

Indications

  • Intra-abdominal Infections
  • Skin and Skin Structure Infections
  • Female Pelvic Infections
  • Community-acquired pneumonia
  • Nosocomial pneumonia

Pharmacology

  • Broad spectrum antibacterial
  • Bactericidal activity
  • Inhibition of septum and cell wall synthesis
  • Beta-lactamase inhibitor

Dosage administration

  • Administered by intravenous infusion over 30 minutes
  • Usual total daily dose for adults is 3.375g every six hours

Interaction

  • Aminoglycosides
  • Probenecid
  • Anticoagulants
  • Vecuronium
  • Methotrexate

Contraindications

  • History of allergic reactions to penicillins, cephalosporins, or beta-lactamase inhibitors

Side effects

  • Adverse events involving skin
  • Gastrointestinal adverse events
  • Immune hypersensitivity reactions
  • Infections-related adverse events

Pregnancy lactation

  • Crosses the placenta
  • Insufficient data in pregnant women
  • Excreted in human milk
  • No information on effects on breastfed child

Precautions warnings

  • Serious hypersensitivity reactions reported
  • Severe cutaneous adverse reactions
  • Hematological effects
  • Nephrotoxicity observed

Special populations

  • Pediatric Use supported by evidence
  • Elderly patients dosage adjustment
  • Renal Impairment dosage adjustment
  • Hepatic Impairment no dosage adjustment

Overdose effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Neuromuscular excitability
  • Convulsions

Therapeutic class

  • Broad spectrum penicillins
  • Other beta-lactam Antibiotics

Reconstitution

  • Administration by intravenous infusion over 30 minutes
  • Specific reconstitution process
  • Storage conditions for reconstituted solution

Storage conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

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