Bumecard 5 mg (Tablet)

Unit Price: ৳ 18.00 (3 x 10: ৳ 540.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Bumetanide
Company Incepta pharmaceuticals ltd
Also available as
Bumecard 1 mg tablet Bumecard 2 mg injection

Indications

  • Edema associated with congestive heart failure
  • Edema associated with hepatic disease
  • Edema associated with renal disease
  • Edema associated with nephrotic syndrome

Pharmacology

  • Loop diuretic
  • Rapid onset
  • Short duration of action
  • Diuretic potency equivalent to furosemide
  • Action on the ascending limb of the loop of Henle
  • Inhibition of sodium reabsorption
  • Inhibition of chloride reabsorption
  • Possible additional action in the proximal tubule
  • Phosphaturia during diuresis

Dosage & Administration

  • Oral dosage: 1mg in the morning, repeated after 6-8 hours if necessary
  • IV Injection dosage: 1-2mg, repeated after 20 minutes if necessary
  • IV Infusion dosage: 2-5mg over 30-60 minutes
  • IM Injection dosage: 1mg initially then adjusted according to response
  • Paediatric use: Safety and effectiveness not established

Interactions

  • Interaction with lithium
  • Interaction with probenecid
  • Interaction with indomethacin
  • Potentiation of antihypertensive drugs
  • No effect on digoxin blood levels
  • No effect on warfarin metabolism

Contraindications

  • Severe hypokalaemia
  • Severe hyponatraemia
  • Anuria
  • Comatose and precomatose states associated with liver cirrhosis
  • Renal failure

Side Effects

  • Muscle cramps
  • Dizziness
  • Hypotension
  • Headache
  • Nausea
  • Other possible effects: ECG changes, musculoskeletal pain, abdominal pain, renal failure, thrombocytopenia

Pregnancy & Lactation

  • Pregnancy Category C
  • No adequate and well-controlled studies in pregnant women
  • Unknown excretion in human milk

Precautions & Warnings

  • Periodic measurement of serum potassium
  • Potential need for potassium supplements or potassium sparing diuretics

Use in Special Populations

  • Safety and effectiveness not established for pediatric patients below 18 years

Overdose Effects

  • Acute profound water loss
  • Volume and electrolyte depletion
  • Dehydration
  • Reduction of blood volume
  • Circulatory collapse
  • Possibility of vascular thrombosis and embolism
  • Treatment consists of fluid and electrolyte replacement

Therapeutic Class

  • Loop diuretics

Storage Conditions

  • Keep below 30°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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