Rovantin 100 mg (Tablet)
Unit Price: ৳ 14.05 (1 x 10: ৳ 140.50)
Strip Price: ৳ 140.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefpodoxime proxetil |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of acute otitis media caused by different microorganisms
- Treatment of pharyngitis/tonsillitis caused by specific bacteria
- Treatment of acute maxillary sinusitis caused by certain strains
- Management of community-acquired pneumonia caused by susceptible bacteria
- Treatment of acute bacterial exacerbation of chronic bronchitis
- Management of skin and skin structure infections caused by specific pathogens
- Management of uncomplicated urinary tract infections
- Treatment of uncomplicated gonorrhea
- Management of rectal gonococcal infections in women
Pharmacology
- Activity against Gram negative and Gram positive bacteria
- Stability to beta lactamases
- Prodrug with active metabolite Cefpodoxime
- Excretion of Cefpodoxime in urine
Dosage & Administration
- Specific dosages for adults and adolescents for various infections
- Specific dosages for infants and pediatric patients for certain infections
- Dosing adjustment for patients with renal dysfunction
- No dose adjustment needed for patients with liver cirrhosis
Interaction
- Reduced peak plasma level and absorption with concomitant use of high doses of antacids or H 2 blockers
- Renal excretion inhibition by probenecid
- Need for close monitoring of renal function when administered with nephrotoxic drugs
Contraindications
- Contraindicated in patients with known allergy to cephalosporin antibiotics
Side Effects
- Occurrence of diarrhea, nausea, skin & vaginal fungal infection, abdominal pain, headache, chest pain, myalgia, dyspepsia, dizziness, vertigo, cough
- Incidence of fungal skin rash is higher in children than in adults
Pregnancy & Lactation
- No evidence of teratogenic or embryocidal effects in animal trials
- Use during pregnancy only if clearly needed
- Excretion of Cefpodoxime in human milk, requiring a decision on breastfeeding
Precautions & Warnings
- Dose reduction in patients with reduction in urinary output due to renal insufficiency
- Caution when administered to patients receiving concurrent treatment with potent diuretics
- Risk of proliferation of non-susceptible organisms with prolonged use
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Instructions for preparing 50 ml suspension with water
- Shake well before each use
- Storage and expiry guidelines for reconstituted suspension
Storage Conditions
- Storage recommendation in a dry place away from light and heat
- Advisory to keep out of the reach of children