Enocef 1 gm/vial (IM Injection)

1 gm vial: ৳ 201.35

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Synovia pharma plc
Also available as
Enocef 1 gm injection Enocef 250 mg injection Enocef 250 mg injection Enocef 500 mg injection Enocef 500 mg injection

Title

  • Enocef Ceftriaxone Injection

Categories

  • Antibiotic
  • Cephalosporin
  • Parenteral medication

Description

  • Indicated for major infections like respiratory infections, otitis media, skin infections, urinary tract infections
  • Third generation broad-spectrum antibiotic
  • Pharmacological action involves interference with bacterial cell wall synthesis
  • Long plasma elimination half-life of 6 to 9 hours
  • Primarily excreted unchanged in urine
  • Highly protein-bound (95%)

Color Options

  • Clear solution for injection

Dosage Form

  • Vial for intravenous or intramuscular administration

Dosage Strengths

  • 250mg
  • 500mg
  • 1g
  • 2g

Age Groups

  • Adults
  • Infants
  • Children

Route of Administration

  • Intravenous
  • Intramuscular

Packaging

  • Single-dose vials
  • Multi-dose vials

Adverse Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy and Lactation

  • Not recommended in pregnancy
  • Caution in lactating mothers

Precautions

  • Risk of anaphylactic shock
  • Regular monitoring of blood picture during prolonged treatment

Special Populations

  • Avoid use in premature and newborn neonates

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Therapeutic Class

  • Third generation Cephalosporins

Drug Interactions

  • No known drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Duration of Therapy

  • 4 to 14 days recommended

Elimination

  • Primarily excreted in urine, remainder in feces

Usual Duration

  • More than 2 days after disappearance of infection signs

Use Cases

  • Lower respiratory tract infections
  • Gonorrhea
  • Prevention of postoperative infections

Administration Instructions

  • Slow injection over 2-4 minutes
  • Check patient tolerance with test dose

Frozen Storage

  • Not recommended

Blood Picture Monitoring

  • Regular intervals during prolonged treatment

Symptomatic Treatment

  • In case of overdose

Gallbladder Side Effects

  • Reversible sludge shadows detected by sonograms

Injection Preparations

  • Dilution in Lidocaine HCI or Water for injection

Dosage Adjustment

  • Based on age and weight

Injection Time

  • 2-4 minutes for intravenous or intramuscular injection
  • 30 minutes for tubing infusion

Hypersensitivity

  • Risk of anaphylactic shock even with thorough patient history

Lactation

  • Caution advised due to low excretion in human milk

Neonatal Use

  • Avoid in premature and newborn neonates

Antidote

  • No specific antidote for overdose

Infection Types

  • Urinary tract infections
  • Meningitis
  • Surgical prophylaxis

Bacterial Coverage

  • Broad-spectrum against Gram-positive and Gram-negative organisms

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