Enocef 250 mg/vial (IM Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Synovia pharma plc |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall. Ceftriaxone has a long plasma elimination half-life of about 6 to 9 hours, and is highly protein bound (95%).
Dosage
- Adult: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Usual duration of therapy: 4 to 14 days
Administration
Preparation for Intramuscular / Intravenous Injections, recommended administration, patient tolerance test and solution stability
Interaction
No drug interactions reported
Contraindications
Patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis
Pregnancy & Lactation
Safety not established in human pregnancy, caution during lactation
Precautions & Warnings
- Anaphylactic shock
- Sonograms of the gallbladder
- Checking blood picture during prolonged treatment
Use in Special Populations
Neonates if premature and newborn (up to 28 days of age)
Overdose Effects
No specific antidote, symptomatic treatment
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of the reach of children