Enocef 500 mg/vial (IM Injection)

500 mg vial: ৳ 150.57

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Synovia pharma plc
Also available as
Enocef 1 gm injection Enocef 1 gm injection Enocef 250 mg injection Enocef 250 mg injection Enocef 500 mg injection

Title and Categories

  • Enocef 3rd Generation Cephalosporins
  • Antibiotic Medication
  • Parenteral Medication

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum bactericidal activity
  • Potent against Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • Stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life
  • High protein binding

Dosage

  • Adult:
    • 1 to 2 gm IV or IM once a day or equally divided doses twice a day
    • Maximum dose: 4 gm/day
  • Uncomplicated gonococcal infections: 250 mg IM as a single dose
  • Surgical prophylaxis: 1 g IV as a single dose 30 to 120 minutes before surgery
  • Infants and Children (01 month or older):
    • 50 to 75 mg/kg IV or IM once a day or equally divided doses twice a day
    • Maximum dose: 2 gm/day
  • Duration of therapy: 4 to 14 days, longer if needed

Administration

  • Intramuscular Injection:
    • Dissolve in Lidocaine HCI 1% injection
  • Intravenous Injection:
    • Dissolve in Water for injection
  • Usual injection period: 2-4 minutes for IM or IV, 30 minutes for tubing infusion

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Pruritus
  • Urticaria
  • Eosinophilia
  • Thrombocytopenia
  • Leucopenia
  • Anemia
  • Neutropenia

Pregnancy & Lactation

Not established in pregnancy, caution during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Caution with gallbladder sludge
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

Avoid in premature and newborn neonates

Overdose Effects

No specific antidote, symptomatic treatment

Storage Conditions

Store below 30°C, away from light and moisture

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