Motilon 10 mg/2 ml (Injection)

2 ml ampoule: ৳ 3.77 (10's pack: ৳ 37.70)

Medicine Details

Category	Details
Generic	Metoclopramide hydrochloride
Company	Synovia pharma plc
Also available as	Motilon 10 mg tablet Motilon 5 mg syrup Motilon 1 mg pediatric drop

Metoclopramide is a medication used to treat symptoms such as nausea and vomiting, as well as diabetic gastroparesis. It comes in various forms including nasal spray, tablets, and injections.

Relief of symptoms in adults with acute and recurrent diabetic gastroparesis
Treatment of symptomatic, documented gastroesophageal reflux in adults
Prevention of nausea and vomiting associated with emetogenic cancer chemotherapy
Facilitates small bowel intubation in adults and pediatric patients

Blocks dopamine receptors
Blocks serotonin receptors in the chemoreceptor trigger zone of the CNS
Enhances the response to acetylcholine of tissue in the upper GI tract
Accelerates gastric emptying without stimulating gastric, biliary, or pancreatic secretions
Increases lower esophageal sphincter tone

Recommended dosage for adults under 65 years of age is 1 spray (15 mg) in one nostril, 30 minutes before each meal and at bedtime (maximum of 4 sprays daily) for 2 to 8 weeks
For gastroesophageal reflux, administer 10 to 15 mg, 30 minutes before each meal and at bedtime (maximum of 60 mg per day) for 4 to 12 weeks
For diabetic gastroparesis, administer 10 mg, 30 minutes before each meal and at bedtime (maximum of 40 mg per day) for 2 to 8 weeks
Dosage for prevention of nausea and vomiting associated with emetogenic cancer chemotherapy and postoperative nausea and vomiting varies based on the emetogenicity of the drugs and the patient's condition

History of tardive dyskinesia or dystonic reaction to metoclopramide
Stimulation of gastrointestinal motility might be dangerous such as in the presence of gastrointestinal hemorrhage, mechanical obstruction, or perforation
Patients with pheochromocytoma or other catecholamine-releasing paragangliomas
Patients with epilepsy
Hypersensitivity to metoclopramide

Avoid concomitant use of other drugs known to cause Tardive Dyskinesia (TD), Other Extrapyramidal Symptoms (EPS), and Neuroleptic Malignant Syndrome (NMS)
Avoid use in patients with Parkinson’s Disease
Discontinue if symptoms occur and seek immediate medical attention
Avoid use in cases of depression and suicidal ideation/suicide