Sanoket 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.38 (1 x 5: ৳ 276.90)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Synovia pharma plc
Also available as
Sanoket 10 mg tablet Sanoket 60 mg injection

Indications

  • Management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Inhibits synthesis of prostaglandins
  • Metabolized in the liver
  • Highly protein bound

Pharmacology

  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours for up to 7 days
  • Injection administration guidelines based on age, weight, and condition
  • Recommended eye drop dosage: 1 drop in each eye 4 times daily

Interaction

  • Increases side effects with other NSAIDs or aspirin
  • Enhances anti-coagulant effect with anti-coagulants
  • Reduces anti-hypertensive effect with beta blockers
  • Increases risk of renal impairment with ACE inhibitors
  • Enhances toxicity of methotrexate

Contraindications

  • Hypersensitivity to drug or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category C
  • Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Exercised caution in patients over 65 years old
  • Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Discontinue eye drops if corneal epithelial breakdown is present

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

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