Sanoket 30 mg/ml (IM/IV Injection)
1 ml ampoule: ৳ 55.38 (1 x 5: ৳ 276.90)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Synovia pharma plc |
| Also available as |
Indications
- Management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation or redness caused by seasonal allergies
Description
- Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
- Inhibits synthesis of prostaglandins
- Metabolized in the liver
- Highly protein bound
Pharmacology
- Inhibits cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours for up to 7 days
- Injection administration guidelines based on age, weight, and condition
- Recommended eye drop dosage: 1 drop in each eye 4 times daily
Interaction
- Increases side effects with other NSAIDs or aspirin
- Enhances anti-coagulant effect with anti-coagulants
- Reduces anti-hypertensive effect with beta blockers
- Increases risk of renal impairment with ACE inhibitors
- Enhances toxicity of methotrexate
Contraindications
- Hypersensitivity to drug or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in females
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Exercised caution in patients over 65 years old
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue eye drops if corneal epithelial breakdown is present
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of reach of children