Epiruba 2 mg/ml (IV Infusion)
10 mg vial: ৳ 900.00
Medicine Details
Category | Details |
---|---|
Generic | Epirubicin hydrochloride |
Company | Drug international ltd |
Title
- Epiruba Injection
Categories
- Cytotoxic Chemotherapy
Description
- Indications as adjuvant therapy in breast cancer patients with axillary node tumor involvement
- Pharmacological action via inhibiting DNA and RNA synthesis
- Dosage administered by intravenous infusion in repeated 3-to 4-week cycles
- Interaction with cardioactive compounds and other cytotoxic drugs
- Contraindications for patients with hypersensitivity to Epirubicin
- Reported side effects including myelosuppression and cardiotoxicity
- Pregnancy Category D, with potential risk to the fetus
- Precautions for handling and disposal, administration only under qualified supervision
- Pediatric uses including dosage adjustments and bone marrow dysfunction considerations
- Storage conditions at 2-8°C, protection from light and children
Dimensions
Color Options
Functions
- Inhibits DNA and RNA synthesis
- Rapid and wide distribution into tissues upon IV administration
- Extensively metabolized by the liver
- Elimination through biliary and urinary excretion
- Patient recovery from acute toxicities before treatment
- Supportive care for potential myelosuppression and cardiotoxicity
- Dosage adjustments based on hematologic and non-hematologic toxicities
- Administration considerations for patients with hepatic and renal impairment
Materials
Technical Specifications
- Total dose of 100 to 120 mg/m² recommended for Epirubicin
- Dosage regimens - CEF-120, FEC-100
- Close monitoring of cardiac function during treatment with cardioactive compounds
- Excretion through biliary and urinary pathways
- Terminal elimination half-life of 30-40 hrs
- Epiruba Day 1 dose reduction in subsequent cycles for certain toxicities
- Storage at 2-8°C to avoid gelled product formation
Design Elements
Usability Features
- Careful baseline assessment of blood counts, serum levels, and cardiac function before treatment
- Administration under supervision of qualified physicians experienced in cytotoxic therapy
- Recommendations for drug handling and preparation
- Observation over time for signs of CHF in case of overdose
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