Epomax 5000 IU (IV/SC Injection)

5000 IU pre-filled syringe: ৳ 1,100.00

Medicine Details

Category Details
Generic Erythropoietin alfa
Company Drug international ltd
Also available as
Epomax 3000 iu injection

Title

Epomax

Categories

  • Medication
  • Erythropoiesis-Stimulating Agent (ESA)

Description

Recombinant human erythropoietin (EPO) expressed in Chinese hamster ovary cells with a 165 amino acid sequence identical to human urinary EPO.

Indications

  • Treating anemia due to Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis
  • Treating anemia due to Zidovudine in HIV-infected patients
  • Treating anemia due to concomitant myelosuppressive chemotherapy
  • Reducing allogeneic RBC transfusions in noncardiac, nonvascular surgery patients
  • Preventing anemia of prematurity in infants with low birth weight and gestational age

DosageGuidelines

  • Evaluate iron stores and nutritional factors before treatment
  • Monitor hemoglobin levels at least weekly when initiating or adjusting therapy
  • Adjust therapy based on hemoglobin rate of rise, decline, and ESA responsiveness
  • Administer Erythropoietin alfa intravenously or subcutaneously based on CKD status

AdministrationInstructions

  • Do not shake or use shaken/frozen Erythropoietin alfa
  • Protect syringe from light
  • Inspect visually for particulate matter or discoloration before administration
  • Discard unused portions

Interaction

May be potentiated by simultaneous therapeutic administration of a haematinic agent like ferrous sulphate

Contraindications

  • Uncontrolled hypertension
  • Serious allergic reactions to Erythropoietin alfa
  • Developed Pure Red Cell Aplasia (PRCA) following treatment with any erythropoietin

SideEffects

  • Hypertension
  • Arthralgia
  • Muscle spasm
  • Pyrexia
  • Dizziness
  • Medical device malfunction
  • Vascular occlusion
  • Upper respiratory tract infection

PregnancyAndLactation

Erythropoietin alfa should be used with caution in pregnant and nursing women

OverdoseEffects

Can cause hemoglobin levels above the desired level and severe hypertension

TherapeuticClass

Drugs for Haemolytic Hypoplastic & Renal Anemia

StorageConditions

Store at 2°C to 8°C, protect from freezing and light

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