Seclogen 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Omeprazole
Company Biogen pharmaceuticals ltd
Also available as
Seclogen 40 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

  • Inhibitor of gastric acid secretion
  • Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
  • Onset of antisecretory effect within one hour
  • Maximum effect within two hours
  • Inhibition of secretion lasts up to 72 hours
  • Gradual return of secretory activity after discontinuation

Dosage

  • Oral administration instructions for various conditions
  • Dosage for NSAID-associated duodenal or gastric ulcer
  • Maintenance dose for recurrent duodenal ulcer
  • Dosage for gastro-esophageal reflux disease
  • Dosage for long-term management of acid reflux disease
  • Dosage for acid-related dyspepsia
  • Dosage for prophylaxis of acid aspiration
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
  • Pediatric use dosage in severe ulcerating reflux esophagitis

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion
  • Reconstitution instructions
  • Intravenous administration precautions
  • Use of freshly prepared solution
  • Instructions for IV infusion dissolution
  • Time frame for use of reconstituted solution

Interaction

  • Effect on absorption of ketoconazole
  • Metabolism through cytochrome P450
  • Effect on elimination of diazepam, phenytoin and warfarin
  • Monitoring recommendations for warfarin or phenytoin
  • Plasma concentration alterations during concomitant administration

Contraindications

  • Known hypersensitivity
  • Exclusion of malignancy before treatment initiation

Side Effects

  • Mild and reversible adverse reactions
  • Reported skin reactions
  • Gastrointestinal reactions
  • Neurological symptoms
  • Psychological symptoms
  • Hematological reactions
  • Liver enzyme alterations

Pregnancy & Lactation

  • Results from prospective epidemiological studies
  • No adverse effects on pregnancy or fetus/child health
  • Use during pregnancy
  • Lack of information on passage into breast milk
  • Recommendation for discontinuation of breastfeeding if essential

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Association with increased risk for osteoporosis-related fractures
  • Atrophic gastritis occurrence in long-term use
  • Methotrexate toxicities with concomitant use

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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