Azbec 100 mcg/puff (Inhaler)

200 metered doses: ৳ 270.00

Medicine Details

Indications

  • Prophylactic management of mild, moderate, or severe asthma in adults or children
  • Effective anti-inflammatory action in the lungs
  • Lower incidence and severity of adverse effects compared to systemic corticosteroids
  • Treatment for patients requiring symptomatic bronchodilator asthma medication
  • For patients with unstable or worsening asthma despite prophylactic therapy or bronchodilator alone
  • For patients with severe chronic asthma
  • Reduction or elimination of requirement for oral corticosteroids
  • Effective preventative treatment for asthma

Pharmacology

  • Produces anti-inflammatory and vasoconstrictor effects
  • Wide range of effects on multiple cell types and mediators involved in inflammation
  • Pro-drug with weak glucocorticoid receptor binding affinity
  • Hydrolyzed to active metabolite beclomethasone-17-monopropionate (B-17-MP)

Dosage

  • For oral inhalation use only
  • Starting dose appropriate to severity of disease
  • Dose adjustment until control is achieved
  • Reduced to minimum effective dose according to individual response
  • Usual starting dose for adults is 200 micrograms twice a day
  • Higher starting dose for more severe cases
  • Total daily dose may be administered as two, three, or four divided doses
  • Starting dose for children is 50 to 100 micrograms two, three, or four times daily in accordance to the response
  • Alternatively, 100 micrograms or 200 micrograms twice daily for children
  • No need to increase the dose in patients with hepatic or renal impairment

Administration

  • Correct and regular use prevents or lessens the severity of asthma attacks
  • Instructions for effective use according to National Asthma Guidelines for Medical Practitioners
  • Recommendations for cleaning the inhaler at least once a week

Contraindications

  • Hypersensitivity to any of the components
  • Special care in patients with active or quiescent pulmonary tuberculosis

Side Effects

  • Systemic effects of inhaled corticosteroids at high doses
  • Possible systemic effects include Cushing's syndrome, Cushingoid features, and adrenal suppression
  • Growth retardation in children and adolescents
  • Decrease in bone mineral density
  • Cataract and glaucoma

Pregnancy & Lactation

  • Inadequate evidence of safety in human pregnancy
  • Administration of corticosteroids to pregnant animals can cause abnormalities of fetal development
  • Therapeutic benefits versus potential hazards to the mother and baby

Precautions & Warnings

  • Proper use of the inhaler and regular use for optimum benefit
  • Patients should be instructed in the proper use of the inhaler and have their technique checked to ensure drug reaches target areas within the lungs

Therapeutic Class

  • Respiratory corticosteroids

Storage Conditions

  • Stored below 30°C, protected from direct sunlight and heat
  • Canister should not be broken, punctured, or burnt
  • Keep away from eyes and out of reach of children

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