Rejoy 7.5 mg (Tablet)
Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00
Medicine Details
Category | Details |
---|---|
Generic | Mirtazapine |
Company | Eskayef pharmaceuticals ltd |
Also available as |
Indications
- Treatment of major depressive disorder (MDD)
Pharmacology
- Enhances central noradrenergic and serotonergic activity
- Acts as an antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
- Potent antagonist of 5- HT<sub>2</sub> and 5-HT<sub>3</sub> receptors
- Moderate peripheral α1-adrenergic antagonist
- Moderate antagonist at muscarinic receptors
- Potent antagonist of histamine (H<sub>1</sub>) receptors
- Metabolized and eliminated via urine and faeces
Dosage & Administration
- Recommended starting dose of 15 mg/day
- Effective dose range of 15 to 45 mg/day
- Elimination half-life of approximately 20 to 40 hours
- Dose changes should be made at intervals of less than 1 to 2 weeks
Interaction
- Clinically significant drug-drug interactions with Monoamine Oxidase Inhibitors (MAOI) & other serotonergic drugs
- May interrupt the metabolism or activity of Carbamazepine, Phenytoin or Cimetidine
- Patient should avoid Alcohol & Diazepam while taking Rejoy
Contraindications
- Contraindicated in patients with known hypersensitivity to Mirtazapine or to any of the excipients
- Concomitant use with Monoamine Oxidase Inhibitors
Side Effects
- Dizziness
- Drowsiness
- Dry mouth
- Increased appetite
- Weight gain
Pregnancy & Lactation
- Pregnancy Category-C
- Patients should notify physician if they become pregnant or intend to become pregnant
- Patients should notify physician if they are breastfeeding an infant
Precautions & Warnings
- Patients, families, and caregivers should be alert to the emergence of certain behaviors and changes in behavior
- Patients should be warned about the risk of developing agranulocytosis
- Rejoy may impair judgment, thinking, and motor skills
- Clinically significant ALT (SGPT) elevations may occur
Therapeutic Class
- Atypical anti-depressant drugs
Storage Conditions
- Store below 30º C
- Keep away from light and moisture
- Keep all medicine out of the reach of children